Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11972 |
Mcl-1 inhibitor 3
|
BCL | Apoptosis |
Mcl-1 inhibitor 3 shows good pharmacokinetic properties and excellent in vivo efficacy without toxicity.Mcl-1 inhibitor 3 is a highly potent and orally activate macrocyclic Mcl-1 inhibitor (Ki= 0.061 nM; IC50=19 nM in an OPM-2 cell viability assay). |