Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T61833 |
Tovinontrine
IMR-687 |
PDE | Metabolism |
Tovinontrine (IMR-687) 是一种针对镰状细胞病治疗设计的强效且选择性的磷酸二酯酶-9 (PDE9) 抑制剂。其展现出高效能,对PDE9A1和PDE9A2的IC 50 值分别为8.19 nM和9.99 nM [1]。 | |||
T24163 |
IMR687
IMR-687,IMR 687 |
||
IMR687 is a PDE9 inhibitor that slows or stops the hydrolysis of cGMP. IMR687 can be regarded as a highly promising drug against Alzheimer's for improving memory. |