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Search Results for " 2-nitroimidazole "

12

抑制剂 & 化合物

1

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T0638	2-Methyl-4-nitroimidazole	Others	Others
	2-Methyl-4-nitroimidazole（2-MNI）是一种杂环化合物，具有抗菌、抗炎和抗肿瘤活性。2-MNI 已被用于多种领域，包括生物化学、药理学和生物技术。
T15202	EF-5 2-Nitroimidazole,EF5	Others	Others
	EF-5 (2-Nitroimidazole) 是一种能够用于鉴定细胞缺氧的缺氧标记试剂。
T0874	Dimetridazole 1, 2-Dimethyl-5-nitroimidazole,1,2-Dimethyl-5-nitroimidazole,二甲硝咪唑	Antibiotic; Parasite	Microbiology/Virology
	Dimetridazole (1, 2-Dimethyl-5-nitroimidazole) 是一种对抗原生动物感染的硝基咪唑类药物。
T3615	Evofosfamide 艾伏磷酰胺,TH-302	Apoptosis; Others	Apoptosis; Others
	Evofosfamide (TH-302) 是一种缺氧激活前药，在缺氧 (N2) 和常氧 (21% O2) 环境下，IC50分别为 10 μM 和 1000 μM。
T2046	Nimorazole Nimorazol,Nitrimidazine,尼莫唑,K-1900,Naxogin,尼莫拉唑	Others; Antibiotic; Parasite	Microbiology/Virology; Others
	Nimorazole (Nimorazol) 是一种 2-硝基咪唑，是一种低氧细胞辐射敏化剂。它具有抗感染，抗滴虫等原生动物的作用。它有头颈癌的研究潜力。
T34705	SR4554 SR 4554
	SR4554 is a fluorine-containing 2-nitroimidazole, designed as a hypoxia marker detectable with 19F magnetic resonance spectroscopy (MRS). SR-4554 has plasma pharmacokinetic and toxicity profiles suitable for use as a hypoxia probe. It can be detected in t
T37524	Ternidazole hydrochloride
	Ternidazole hydrochloride, a hydroxymetabolite derived from nitroimidazole, exhibits antiprotozoic properties [1][2].
T33698	NLA 1 NLA1,NLA-1
	NLA 1是一种生物还原性化合物，一种嵌入靶向DNA 的2-硝基咪唑放射增敏剂。NLA-1以类似于9-aminoacridine 的亲和力可逆地结合DNA，并且作为细胞毒素的效力大约是MISO 的1000倍。
T70813	DTP348
	DTP348 is an oral dual CAIX inhibitor/ radiosensitizer. DTP 348 is an oral dual drug with two mechanisms of action: (1). carbonic anhydrase IX inhibitor which acidifies the intracellular pH through the sulfamide components; (2). radio sensitizer of hypoxic cells through its 5-nitroimidazole moiety.
T69714	Etanidazole
	Etanidazole (SR-2508) is a 2-nitroimidazole drug with radiosensitizing properties. Etanidazole depletes glutathione and inhibits glutathione transferase, thereby enhancing the cytotoxicity of ionizing radiation. This agent may also be useful as an imaging agent for identifying hypoxic, drug-resistant regions of primary tumors or metastases. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
T40605	N-(2-Hydroxyethyl)oxamic acid
	N-(2-hydroxyethyl)-oxamic acid, a compound derived from the reduction of Metronidazole, can result from either chemical processes or through interaction with intestinal bacteria. Metronidazole itself is a nitroimidazole antibiotic with a broad range of efficacy against protozoans, as well as both Gram-negative and Gram-positive anaerobic bacteria.
T75285	Metronidazole hydrochloride
	Metronidazole hydrochloride (SC 326421) 是一种有口服活性的硝基咪唑抗生素，适用于厌氧微生物感染的研究。该化合物能穿越血脑屏障，长期服用可能引发炎症和骨骼肌收缩问题。

化合物

2-Methyl-4-nitroimidazole

Cat.No: T0638

Target: Others

Cat.No: T15202

Synonym: 2-Nitroimidazole,EF5

Target: Others

Cat.No: T0874

Synonym: 1, 2-Dimethyl-5-nitroimidazole,1,2-Dimethyl-5-nitroimidazole,二甲硝咪唑

Target: Antibiotic, Parasite

Cat.No: T3615

Synonym: 艾伏磷酰胺,TH-302

Target: Apoptosis, Others

Cat.No: T2046

Synonym: Nimorazol,Nitrimidazine,尼莫唑,K-1900,Naxogin,尼莫拉唑

Target: Others, Antibiotic, Parasite

Cat.No: T34705

Synonym: SR 4554

Ternidazole hydrochloride

Cat.No: T37524

Cat.No: T33698

Synonym: NLA1,NLA-1

Cat.No: T70813

Cat.No: T69714

N-(2-Hydroxyethyl)oxamic acid

Cat.No: T40605

Metronidazole hydrochloride

Cat.No: T75285

Cat. No.	Product Name	Target	Signaling Pathways
T6402	Azomycin 2-Nitroimidazole,2-硝基咪唑,Ro 05-9129,Amicin	Antibacterial; Antibiotic	Microbiology/Virology
	Azomycin (Ro 05-9129) 是一种可抑制有氧革兰氏阳性菌和革兰氏阴性菌的生长的抗生素。

天然产物

Cat.No: T6402

Synonym: 2-Nitroimidazole,2-硝基咪唑,Ro 05-9129,Amicin

Target: Antibacterial, Antibiotic

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