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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7084 |
2-Bromo-4'-hydroxyacetophenone
SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide,2-溴-4'-羟基苯乙酮 |
Phosphatase | Metabolism |
2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) 是一种PTP1B 的有效抑制剂,其Ki=42 μM。 | |||
T10143 | 4-Hydroxyacetophenone oxime | Others | Others |
4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol). Acetaminophen is a potent COX-2 and hepatic NAT2 inhibitor and used antipyretic and analgesic drug. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TCS1856 |
2'-Hydroxyacetophenone
2'-羟基苯乙酮,o-Hydroxyacetophenone,o-Acetylphenol,2-Acetylphenol,O-Hydroxyphenyl Methyl Ketone |
CYP19A1 | Others |
2'-Hydroxyacetophenone (o-Hydroxyacetophenone) 是有机合成中的砌块,存在于番茄,决明子,炒牛肉,朗姆酒,威士忌,可可,咖啡和红茶中。它是调味成分,存在于酒精饮料中。 | |||
T3760 |
2'-Hydroxy-5'-methoxyacetophenone
2'-羟基-5'-甲氧基苯乙酮,5-Methoxy-2-hydroxyacetophenone |
Others | Others |
2'-Hydroxy-5'-methoxyacetophenone (5-Methoxy-2-hydroxyacetophenone) 是一种活性生化剂。 | |||
T7917 |
4'-Hydroxychalcone
4-羟基查耳酮,4′-羟基查耳酮,2-Benzal-4-Hydroxyacetophenone |
Proteasome | Proteases/Proteasome; Ubiquitination |
4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) 是从甘草根中分离的一种查尔酮,具有保护肝脏的作用。它能诱导大鼠离体肝线粒体囊泡快速释放钾,并引起其线粒体呼吸控制和氧化磷酸化衰退。它能通过抑制蛋白酶体 (proteasome),抑制TNFα 诱导的 NF-κB 活性。 |