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Cat. No. Product Name Target Signaling Pathways
T15818 LY367385

FXR Metabolism
LY367385 is a highly effective and selective mGluR1a antagonist. LY367385 has neuroprotective, anticonvulsant, and antiepileptic effects. Compared with > 100 μM for mGlu5a, LY367385 has an IC50 of 8.8 μM for inhibits of quisqualate-induced phosphoinositide (PI) hydrolysis.
T60355 LY367385 hydrochloride

LY367385 hydrochloride 是一种高效且选择性的mGluR1a 拮抗剂,抑制喹喹啉诱导的磷酸肌醇水解的IC50值为 8.8 μM,而对 mGlu5a 的IC50值大于 100 μM。LY367385 hydrochloride 具有神经保护,抗惊厥和抗癫痫作用。
T39406 (±)-LY367385

(±)-LY367385

(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist. LY367385 exhibits a high inhibitory activity against quisqualate-induced phosphoinositide (PI) hydrolysis, with an IC50 value of 8.8 μM. In contrast, its inhibitory activity against mGlu5a is greater than 100 μM.

化合物

LY367385
Cat.No: T15818
Synonym:
Target: FXR
LY367385 hydrochloride
Cat.No: T60355
Synonym:
Target:
(±)-LY367385
Cat.No: T39406
Synonym: (±)-LY367385
Target:
TargetMol Loading
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