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Cat. No. Product Name Target Signaling Pathways
T4641 Branaplam

LMI 070,NVS-SM1

Others; Potassium Channel; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Others
Branaplam (LMI 070) 是一种高效、选择性和口服活性的小分子 SMN2 剪接调节剂,对 SMN 的 EC50为 20 nM。它可提高全长 SMN 蛋白并延长其生存期,也抑制 hERG,IC50为 6.3 μM。
T26893 Branaplam mesylate (1562338-42-4 free base)

LMI070,Branaplam mesylate,LMI 070,LMI-070

Branaplam is a highly potent, selective and orally active SMN2 splicing modulator. Branaplam increases the amount of functional SMN protein produced by the SMN2 gene through modifying its splicing.

化合物

Branaplam
Cat.No: T4641
Synonym: LMI 070,NVS-SM1
Target: Others, Potassium Channel, DNA/RNA Synthesis
Branaplam mesylate (1562338-42-4 free base)
Cat.No: T26893
Synonym: LMI070,Branaplam mesylate,LMI 070,LMI-070
Target:
TargetMol Loading
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