Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22559 |
Alendronate sodium
|
Others | Others |
The compound binds and blocks farnesyl diphosphate synthase in the HMG-CoA pathway (IC50 = 460 nM for recombinant human FPPS). It causes macrophage apoptosis and inhibits prenylation and sterol biosynthesis in purified osteoclasts. | |||
T6373 |
Alendronate sodium hydrate
G-704650,Alendronate,MK 217,Alendronate sodium trihydrate,阿仑膦酸钠,G-704650 Adronat,Fosamax |
Transferase | Metabolism |
Alendronate sodium hydrate (MK 217) 是 farnesyl diphosphate synthase 抑制剂(IC50:460 nM)。 | |||
T7469 |
Alendronic Acid
alendronate,阿仑膦酸 |
Others | Others |
Alendronic Acid (alendronate) 是法呢基二磷酸合酶(FDPS)抑制剂,是一种双膦酸盐。它能够抑制破骨细胞介导的骨吸收,对绝经后骨质疏松症,恶性高钙血症和 Paget 病具有疗效。 |