Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T14338 |
Atabecestat
JNJ-54861911 |
BACE | Neuroscience |
Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction and it is tolerated and displays a sustained pharmacokinetic (PK) and |