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Cat. No.	Product Name	Target	Signaling Pathways
T10160	11β-HSD1-IN-1	Dehydrogenase	Metabolism
	11β-HSD1-IN-1是1β 羟类固醇脱氢酶Ⅰ型（11β-HSD1，IC50:52nM）的抑制剂，用于治疗疼痛。
T60149	11β-HSD1-IN-11	Dehydrogenase	Metabolism
	11β-HSD1-IN-11 是一种有效的、具有竞争性的 11- β-羟基类固醇脱氢酶1 (11β-HSD1)抑制剂，对大鼠和人的 11β-HSD1具有抑制作用，IC50 分别为 0.34 μM 和 0.13 μM。11β-HSD1- in -11是一种作为的化合物。11β-HSD1-IN-11是一种参与调节各种生理过程的激素，例如代谢、炎症和应激反应。11β-HSD1-IN-11是治疗代谢紊乱、肥胖和某些炎症状况的潜在化合物。
T60203	INCB13739
	INCB13739是一种具有口服活性、高效、选择性及组织特异性的11β-HSD1抑制剂，对11β-HSD1酶的IC50为3.2 nM，对11β-HSD1 PBMC的IC50为1.1 nM。适用于2型糖尿病(T2DM)和肥胖的研究。
T61593	11β-HSD1-IN-6
	11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs). These enzymes are responsible for catalyzing the conversion of the active glucocorticoids, corticosterone or cortisol, to their respective inactive forms, 11-dehydrocorticosterone (11-DHC) and cortisone. The compound 11β-HSD1-IN-6 specifically targets and inhibits 11β-HSD-1, effectively modulating the interconversion of these glucocorticoids. [1]
T80817	WAY-328127
	WAY-328127是一种活性分子，适用于生化反应研究。
T70763	KR-67607
	KR-67607, also known as NTX-101 is novel selective 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor. KR-67607 decreased 4-hydroxynonenal expression and increased antioxidant and mucus secretion in BAC-treated rat eyes. KR-67607 showed its protective effects against ischemia-reperfusion-induced eye injury. KR-67607 effectively reduced cortisol levels in mouse eyes and maintained the trabecular meshwork (TM) structure in the presence of transient ischemic stress. Furthermore, KR-67607 rever...