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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T70808 Cabazitaxel-d6

Cabazitaxel-d6 is a deuterium labeled cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel binds to and stabilizes tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Unlike other taxane compounds, this agent is a poor substrate for the membrane-associated, multidrug resistance...

化合物

Cabazitaxel-d6
Cat.No: T70808
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T2197 10-Deacetylbaccatin III

10-脱乙酰巴卡丁 III,10-脱乙酰基巴卡丁III

Others Others
10-Deacetylbaccatin-III 是一种紫杉醇类似物制剂的中间体,具有抗癌活性。
TN3251 7-Xylosyl-10-deacetylbaccatin III

Others Others
7-Xylosyl-10-deacetylbaccatin III is a natural product from Taxus brevifolia.
T83435 19-Hydroxy-10-deacetylbaccatin III

19-Hydroxy-10-deacetylbaccatin III (compound 13) 是紫杉烷类化合物,显示出潜在的抗肿瘤作用。在 A498 和 NCI-H226 细胞系中,此化合物表现出轻微的细胞毒性效应。研究指出,当浓度为 30 μg/mL 时,19-Hydroxy-10-deacetylbaccatin III 对 A498 细胞和 NCI-H226 细胞的抑制率为 16.6% 和 32%。
T2543 Cabazitaxel

XRP6258,卡巴他塞,RPR-116258A,TXD 258,taxoid XRP6258

Microtubule Associated; Autophagy Autophagy; Cytoskeletal Signaling
Cabazitaxel (taxoid XRP6258) 是一种紫杉烷类的抗肿瘤剂,可用于治疗多西他赛失败后的去势抵抗性转移性前列腺癌。

天然产物

10-Deacetylbaccatin III
Cat.No: T2197
Synonym: 10-脱乙酰巴卡丁 III,10-脱乙酰基巴卡丁III
Target: Others
7-Xylosyl-10-deacetylbaccatin III
Cat.No: TN3251
Synonym:
Target: Others
19-Hydroxy-10-deacetylbaccatin III
Cat.No: T83435
Synonym:
Target:
Cabazitaxel
Cat.No: T2543
Synonym: XRP6258,卡巴他塞,RPR-116258A,TXD 258,taxoid XRP6258
Target: Microtubule Associated, Autophagy
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