Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T50110 |
CD532
|
Aurora Kinase | Cell Cycle/Checkpoint; Chromatin/Epigenetic |
CD532 是一种高效的 Aurora A 激酶抑制剂,IC50 值为 45 nM。CD532 可阻断 Aurora A 激酶活性,驱动 MYCN 降解,可以直接与 AURKA 相互作用并诱导整体构象转变。CD532 可用于研究癌症。 | |||
T36932 | CD532 hydrochloride | ||
CD532 hydrochloride is a potent inhibitor of Aurora A kinase, having an IC50 of 45 nM. It not only blocks the activity of Aurora A kinase but also facilitates the degradation of the protein MYCN. Furthermore, CD532 hydrochloride interacts directly with AURKA, inducing a significant conformational change. Its utility in cancer research has been demonstrated [1][2]. |