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Search Results for " α-glucosidase-in-6 "

4

抑制剂 & 化合物

4

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T63310	α-Glucosidase-IN-6
	α-Glucosidase-IN-6 是 α-glucosidase 的竞争性抑制剂 (IC50: 5.69 μM)，表现出抗糖尿病的研究潜力。
T80715	α-Amylase/α-Glucosidase-IN-6
	α-Amylase/α-Glucosidase-IN-6 (compound 5j) 是一种对α-amylase和α-glucosidase具有双重抑制作用的有效化合物，其IC50s分别为17.0 µM和40.1 µM。该化合物还表现出抗高血糖活性。
T10755L	Celgosivir MX3253,MBI 3253,6 O-butanoyl castanospermine,MDL 28574	Glucosidase	Metabolism
	Celgosivir (6 O-butanoyl castanospermine) 是 α-葡萄糖苷酶 I (α-glucosidase I) 抑制剂，在体外实验中的 IC50 值为 1.27 μM。
T37843	Australine (hydrochloride)
	Australine is a pyrrolizidine alkaloid originally isolated fromC. australethat has enzyme inhibitory activities.1,2,3It is an inhibitor of glucoamylase (IC50= 5.8 μM) that also inhibits glucosidase I, sucrase, maltase, andA. nigerα-glucosidase (IC50s = 20, 28, 35, and 28 μM, respectively).2,3Australine is selective for these enzymes over glucosidase II, α- and β-mannosidase, and α- and β-galactosidase up to 500 μM, β-glucosidase, with only 5% inhibition at 66 μM, as well as isomaltase and trehal...

化合物

α-Glucosidase-IN-6

Cat.No: T63310

α-Amylase/α-Glucosidase-IN-6

Cat.No: T80715

Cat.No: T10755L

Synonym: MX3253,MBI 3253,6 O-butanoyl castanospermine,MDL 28574

Target: Glucosidase

Australine (hydrochloride)

Cat.No: T37843

Cat. No.	Product Name	Target	Signaling Pathways
TN1488	Chrysin 6-C-glucoside 8-C-arabinoside	Others	Others
	Chrysin 6-C-glucoside 8-C-arabinoside 是α±-葡萄糖苷酶抑制剂，α±-葡萄糖苷酶抑制剂广泛用于2型糖尿病的治疗。
TN1487	Chrysin 6-C-arabinoside 8-C-glucoside	Others	Others
	Chrysin 6-C-arabinoside 8-C-glucoside 是α±-葡萄糖苷酶抑制剂，α±-葡萄糖苷酶抑制剂广泛用于2型糖尿病的治疗。
T6S1371	Isovitexin Homovitexin,Saponaretin,Apigenin-6-C-Glucoside,异牡荆黄素	NF-κB; JNK; Glucosidase	MAPK; Metabolism; NF-κB
	Isovitexin (Apigenin-6-C-Glucoside) 是从亚洲水稻种得到的一种黄酮，具有抗氧化和抗炎活性。它的作用与JNK1/2的抑制剂类似，抑制NF-κB 的活化。
T37774	Thielavin A
	Thielavin A is a fungal metabolite originally isolated from T. terricola that is related to thielavin B . Thielavin A inhibits COX, blocking both the conversion of arachidonic acid to prostaglandin H2 and the conversion of PGH2 to PGE2 . Thielavin A also inhibits glucose-6-phosphatase in rat liver microsomes (IC50 = 4.6 μM). It is a non-competitive inhibitor of α-glucosidase from S. cerevisiae (IC50 = 23.8 μM; Ki = 27.8 μM).

天然产物

Chrysin 6-C-glucoside 8-C-arabinoside

Cat.No: TN1488

Target: Others

Chrysin 6-C-arabinoside 8-C-glucoside

Cat.No: TN1487

Target: Others

Cat.No: T6S1371

Synonym: Homovitexin,Saponaretin,Apigenin-6-C-Glucoside,异牡荆黄素

Target: NF-κB, JNK, Glucosidase

Cat.No: T37774

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