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9

抑制剂 & 化合物

16

天然产物

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Cat. No. Product Name Target Signaling Pathways
T37898 UDP-α-D-Glucose (sodium salt hydrate)

UDP-α-D-Glucose is an endogenous nucleotide sugar involved in glycosyltransferase reactions in metabolism. It has been shown to bind the P2Y14receptor (EC50= 0.35 μM), an atypical P2Y receptor involved in the activation of dendritic cells and glial cells.1It can also bind to and activate GPR17, inducing oligodendrocyte differentiation at a maximal concentration of 100 μM.2 1.Jacobson, K.A., Ivanov, A.A., de Castro, S., et al.Development of selective agonists and antagonists of P2Y receptorsPurin...
T35416 α-D-Glucose-1-phosphate (sodium salt hydrate)

α-D-Glucose-1-phosphate is an intermediate in glycogen metabolism.1,2It is a precursor in the biosynthesis of UDP-glucose, the glucose donor in glycogen biosynthesis.2α-D-Glucose-1-phosphate can be formed during glycogen breakdownviaphosphorolytic cleavage of glycogen by glycogen phosphorylase.1It can be converted to glucose-6-phosphate by phosphoglucomutase. α-D-Glucose-1-phosphate is combined with CTP by α-D-glucose-1-phosphate cytidylyltransferase to form CDP-glucose in the first step of CDP-...
T37285 1-thio-β-D-Glucose Tetraacetate

1-thio-β-D-Glucose tetraacetate is a building block.1,2It has been used in the synthesis of aromatic glucosinolates with anti-inflammatory activity, as well as glucosylated poly(pentafluorostyrene) derivatives for coating magnetic iron oxide nanoparticles. 1.Vo, Q.V., Trenerry, C., Rochfort, S., et al.Synthesis and anti-inflammatory activity of aromatic glucosinolatesBioorg. Med. Chem.21(19)5945-5954(2013) 2.Babiuch, K., Wyrwa, R., Wagner, K., et al.Functionalized, biocompatible coating for supe...
T37899 UDP-β-D-Glucose (sodium salt)

UDP-β-D-Glucose is the stereoisomer of UDP-α-D-glucose (sodium salt) . The activities of the UDP-β-D-glucose isomer are not known.
T37786 1-thio-β-D-Glucose (sodium salt)

1-thio-β-D-Glucose is an analog of β-D-glucose in which sulfur replaces the hydroxyl group at the one position. The thiol group allows diverse chemical reactions, including click chemistry and polymerization. 1-thio-β-D-Glucose can be labeled with technetium-99m for analytical and diagnostic procedures. It can also be used as a substrate for glucose oxidase, which leads to the production of 1-thio-β-D-gluconic acid.
T19596 UDP-GlcNAc Disodium Salt

Uridine 5′-diphospho-N-acetylglucosamine,5′-二磷酸尿嘧啶核苷-N-乙酰半乳糖胺二钠盐,UDP-α-D-N-Acetylglucosamine Disodium Salt

Others Others
UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) 是一种 O-GlcNAc 转移酶 (OGT) 的供体底物。
T37835 2-Chloro-4-nitrophenyl-α-D-glucopyranoside

Carbohydrates conjugated with 2-chloro-4-nitrophenyl (CNP) serve as chromogenic substrates in assays for enzymes that release CNP from the conjugated carbohydrate. For example, CNP-β-D-maltoheptaoside and CNP-α-maltotrioside are chromogenic substrates for α-amylase. 2-Chloro-4-nitrophenyl-α-D-glucopyranoside is a conjugate of CNP and α-D-glucose. The related conjugate between CNP and β-D-glucose, 2-chloro-4-nitrophenyl β-D-glucopyranoside, is used as a chromogenic substrate for glycosyltransfera...
T41028 α-Glucosidase

α-D-Glucosidase,α-葡萄糖苷酶

α-Glucosidase (α-D-Glucosidase) is a carbohydrate hydrolyzing enzyme that catalyzes the release of α-glucose from the non-reducing end of the substrate. It plays a vital role in facilitating glucose absorption by the small intestine. Inhibiting α-Glucosidase effectively manages non-insulin-dependent diabetes mellitus (NIDDM).
T76103 Sucrose phosphorylase

Sucrose phosphorylase 是一种bacterium转葡萄糖苷酶,专门催化蔗糖与磷酸盐反应形成 α-D-葡萄糖-1-磷酸和 D-果糖。此外,该酶通过glucosylation作用可以水解产生 α-D-葡萄糖或将glucosyl group转移至目标hydroxyl group,进而合成新的 α-D-葡萄糖苷。它对底物与产物的hydrolase活性表现出较弱的反应性。

化合物

UDP-α-D-Glucose (sodium salt hydrate)
Cat.No: T37898
Synonym:
Target:
α-D-Glucose-1-phosphate (sodium salt hydrate)
Cat.No: T35416
Synonym:
Target:
1-thio-β-D-Glucose Tetraacetate
Cat.No: T37285
Synonym:
Target:
UDP-β-D-Glucose (sodium salt)
Cat.No: T37899
Synonym:
Target:
1-thio-β-D-Glucose (sodium salt)
Cat.No: T37786
Synonym:
Target:
UDP-GlcNAc Disodium Salt
Cat.No: T19596
Synonym: Uridine 5′-diphospho-N-acetylglucosamine,5′-二磷酸尿嘧啶核苷-N-乙酰半乳糖胺二钠盐,UDP-α-D-N-Acetylglucosamine Disodium Salt
Target: Others
2-Chloro-4-nitrophenyl-α-D-glucopyranoside
Cat.No: T37835
Synonym:
Target:
α-Glucosidase
Cat.No: T41028
Synonym: α-D-Glucosidase,α-葡萄糖苷酶
Target:
Sucrose phosphorylase
Cat.No: T76103
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T4924 α-D-Glucose-1-phosphate disodium

A-D-葡萄糖-1-磷酸-二钠盐,α-D-Glucose 1-phosphate disodium salt hy,α-D-Glucopyranose 1-phosphate

Others; Endogenous Metabolite Metabolism; Others
α-D-Glucose 1-phosphate disodium salt hydrate 是合成葡萄糖醛酸的起始原料。它可用作心脏病研究所必需的细胞抑制剂、抗生素、免疫抑制剂和循环系统研究材料。
T4884 alpha-D-glucose

α-D-Glucose,α-葡萄糖,alpha-Glucose,α-Dextrose

Others; Endogenous Metabolite Metabolism; Others
alpha-D-glucose (α-Dextrose) 是内源性代谢产物的一种。
T0581 Isomaltose

D-Isomaltose,6-O-α-D-Glucopyranosyl-D-glucose,低聚异麦芽糖900

Others; Endogenous Metabolite Metabolism; Others
Isomaltose (D-Isomaltose) 是由两个葡萄糖组成的麦芽糖类似物,能够作为蔗糖的替代物,适合于糖尿病患者及有糖尿病倾向的人群。
T72172 4,6-O-Ethylidene-α-D-glucose

Ethylidene-glucose

4,6-O-ethylidene-α-D-glucose (Ethylidene-glucose) 是一种葡萄糖衍生物,是竞争性的葡萄糖转运蛋白 1 (GLUT1) 面部结合部位抑制剂,对野生型 2-脱氧-D-葡萄糖转运的 Ki 值为 12 mM。
T4743 Uridine 5′-diphosphoglucose disodium salt

二磷酸尿苷葡萄糖二钠盐,UDP-Glucose sodium salt,UDPG sodium salt,UDP-α-D-Glucose sodium salt,Uridine 5'-diphosphoglucose disodium sal

Endogenous Metabolite; P2Y Receptor GPCR/G Protein; Metabolism; Neuroscience
Uridine 5′-diphosphoglucose disodium salt (UDP-Glucose sodium salt) 是一种内源性核苷酸糖,参与代谢中的糖基转移酶反应。它是 P2Y14 受体的激动剂,EC50为 0.35 μM。
T35415 α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)

α-D-Glucose-1,6-bisphosphate is abis-phosphorylated derivative of α-D-glucose that has roles in carbohydrate metabolism.1It is the product of the reaction of glucose-1- or 6-phosphate with glucose-1,6-bisphosphate synthase (PGM2LI) in the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate.2It is also a cofactor for the bacterial enzyme phosphopentomutase.3,4α-D-Glucose-1,6-bisphosphate has been used in the study of carbohydrate metabolism. 1.Beitner, R.Regulation of carbohydrate metabol...
T73925 α-D-Glucose-1-phosphate disodium hydrate

α-D-Glucose-1-phosphate disodium hydrate 为合成葡萄糖醛酸的初始原料之一,同时,在心脏病研究领域,亦被广泛应用作为细胞抑制剂、抗生素、免疫抑制剂与循环系统研究的关键材料。
T81992 Kaempferol 3,7-bis(α-L-rhamnose-D-glucose)

Kaempferol 3,7-bis(α-L-rhamnose-D-glucose) (化合物1)为Euonymus fortune中存在的黄酮苷。
T40485 Limocitrin 3-β-D-glucose

Limocitrin 3-β-D-glucose is a flavonoid glycoside.
T83478 1,2,6-Tri-O-galloyl-β-D-glucose

1,2,6-Tri-O-galloyl-β-D-glucose 是可以从Sanguisorba officinalis中提取的化合物。
T3145 D-(+)-Trehalose dihydrate

Trehalose dihydrate,α,α-Trehalose dihydrate,alpha,alpha-Trehalose dihydrate,D-Trehalose dihydrate,二水合海藻糖

Others Others
D-(+)-Trehalose dihydrate (α,α-Trehalose dihydrate) 是分离自 Saccharomyces cerevisiae 中,可用作食品成分和药物赋形剂。
T2713 Stachyose tetrahydrate

Stachyose,D-Stachyose tetrahydrate,水苏糖

Apoptosis; Others Apoptosis; Others
Stachyose tetrahydrate (D-Stachyose tetrahydrate) 是一种功能性低聚糖,可在肠道内产生有益物质或通过促进益生菌的增殖,间接防止结肠癌细胞生长,可作为益生元。
T2914 D-Melibiose

Galalpha1-6Glcbeta,蜜二糖,Melibiose

Others; Endogenous Metabolite Metabolism; Others
D-Melibiose (Galalpha1-6Glcbeta) 是一种还原性二糖,由一个半乳糖和一个糖基组成 (1-6) 糖苷链构成的。
T4875 Palatinose hydrate

6-O-α-D-Glucopyranosyl-D-fructose, Isoma,帕拉金糖水合物

Others; Endogenous Metabolite Metabolism; Others
Palatinose hydrate (6-O-α-D-Glucopyranosyl-D-fructose, Isoma) 是内源性代谢产物的一种。
T8144 Raffinose

Melitose,Melitriose,棉子糖

Others; Endogenous Metabolite Metabolism; Others
Raffinose (Melitriose) 是不能够消化的短链寡糖,是由半乳糖,葡萄糖和果糖组成的三糖,能够在许多植物中找到。它能够被 α-半乳糖苷酶 (α-GAL) 水解为 D-半乳糖和蔗糖。
T78506 α-Lactose hydrate

α-D-Lactose hydrate

α-Lactose (hydrate)(α-D-Lactose (hydrate))是哺乳动物乳汁的主要碳水化合物,由葡萄糖和半乳糖构成,并有α和β两种异构体。它广泛应用于食品和制药行业,常作为松散剂或凝聚剂,也用于稀释色素、香料或酶。

天然产物

α-D-Glucose-1-phosphate disodium
Cat.No: T4924
Synonym: A-D-葡萄糖-1-磷酸-二钠盐,α-D-Glucose 1-phosphate disodium salt hy,α-D-Glucopyranose 1-phosphate
Target: Others, Endogenous Metabolite
alpha-D-glucose
Cat.No: T4884
Synonym: α-D-Glucose,α-葡萄糖,alpha-Glucose,α-Dextrose
Target: Others, Endogenous Metabolite
Isomaltose
Cat.No: T0581
Synonym: D-Isomaltose,6-O-α-D-Glucopyranosyl-D-glucose,低聚异麦芽糖900
Target: Others, Endogenous Metabolite
4,6-O-Ethylidene-α-D-glucose
Cat.No: T72172
Synonym: Ethylidene-glucose
Target:
Uridine 5′-diphosphoglucose disodium salt
Cat.No: T4743
Synonym: 二磷酸尿苷葡萄糖二钠盐,UDP-Glucose sodium salt,UDPG sodium salt,UDP-α-D-Glucose sodium salt,Uridine 5'-diphosphoglucose disodium sal
Target: Endogenous Metabolite, P2Y Receptor
α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)
Cat.No: T35415
Synonym:
Target:
α-D-Glucose-1-phosphate disodium hydrate
Cat.No: T73925
Synonym:
Target:
Kaempferol 3,7-bis(α-L-rhamnose-D-glucose)
Cat.No: T81992
Synonym:
Target:
Limocitrin 3-β-D-glucose
Cat.No: T40485
Synonym:
Target:
1,2,6-Tri-O-galloyl-β-D-glucose
Cat.No: T83478
Synonym:
Target:
D-(+)-Trehalose dihydrate
Cat.No: T3145
Synonym: Trehalose dihydrate,α,α-Trehalose dihydrate,alpha,alpha-Trehalose dihydrate,D-Trehalose dihydrate,二水合海藻糖
Target: Others
Stachyose tetrahydrate
Cat.No: T2713
Synonym: Stachyose,D-Stachyose tetrahydrate,水苏糖
Target: Apoptosis, Others
D-Melibiose
Cat.No: T2914
Synonym: Galalpha1-6Glcbeta,蜜二糖,Melibiose
Target: Others, Endogenous Metabolite
Palatinose hydrate
Cat.No: T4875
Synonym: 6-O-α-D-Glucopyranosyl-D-fructose, Isoma,帕拉金糖水合物
Target: Others, Endogenous Metabolite
Raffinose
Cat.No: T8144
Synonym: Melitose,Melitriose,棉子糖
Target: Others, Endogenous Metabolite
α-Lactose hydrate
Cat.No: T78506
Synonym: α-D-Lactose hydrate
Target:
TargetMol Loading
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