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抑制剂 & 化合物

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T7507	γ-L-Glutamyl-L-alanine	Others; Endogenous Metabolite	Metabolism; Others
	γ-L-Glutamyl-L-alanine 由γ-谷氨酸和丙氨酸组成，是CRF21（γ-谷氨酰环转移酶，GGCT）的底物。
T7507L	γ-L-Glutamyl-L-alanine acetate (5875-41-2 Free base)

T38214	1-Deoxysphingosine (m18:1(4E)) 1-Deoxysphingosine (m18:1(4E))
	1-Deoxysphingosine (m18:1(4E)) is an atypical sphingolipid that contains a double bond at the 4E native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 Plasma levels of 1-deoxysphingosine (m18:1(4E)) are increased in patients with chronic idiopathic axonal neuropathy (CIAP) and diabetic distal symmetrical polyneuropathy (DSPN).3 \|1. Steiner, R., Saied, E.M., Othman, A., et al. Elucidating the chemica...
T38280	C22 dihydro 1-Deoxyceramide (m18:0/22:0) C22 dihydro 1-Deoxyceramide (m18:0/22:0)
	C22 dihydro 1-Deoxyceramide (m18:0/22:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 C22 dihydro 1-Deoxyceramide (m18:0/22:0) has been found in mouse embryonic fibroblasts (MEFs) following application of 1-deoxysphinganine alkyne or 1-deoxysphinganine-d3.3 It has also been found as the most prevalent dihydro...
T38284	C24 dihydro 1-Deoxyceramide (m18:0/24:0) C24 dihydro 1-Deoxyceramide (m18:0/24:0)
	C24 dihydro 1-Deoxyceramide (m18:0/24:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 C24 dihydro 1-Deoxyceramide (m18:0/24:0) has been found in mouse embryonic fibroblasts (MEFs) following application of 1-deoxysphinganine alkyne or 1-deoxysphinganine-d3.3 It has also been found in mouse brain, spinal cord, ...

化合物

γ-L-Glutamyl-L-alanine

Cat.No: T7507

Synonym:

Target: Others, Endogenous Metabolite

γ-L-Glutamyl-L-alanine acetate (5875-41-2 Free base)

Cat.No: T7507L

Synonym:

Target:

1-Deoxysphingosine (m18:1(4E))

Cat.No: T38214

Synonym: 1-Deoxysphingosine (m18:1(4E))

Target:

C22 dihydro 1-Deoxyceramide (m18:0/22:0)

Cat.No: T38280

Synonym: C22 dihydro 1-Deoxyceramide (m18:0/22:0)

Target:

C24 dihydro 1-Deoxyceramide (m18:0/24:0)

Cat.No: T38284

Synonym: C24 dihydro 1-Deoxyceramide (m18:0/24:0)

Target:

Cat. No.	Product Name	Target	Signaling Pathways
T4811	D-Alanine D-α-Alanine,Ba 2776,(R)-Alanine,D-丙氨酸,(R)-2-Aminopropionic acid	Chloride channel; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism
	D-Alanine ((R)-Alanine) 是一种GlyR 和PMBA 的弱激动剂，其对GlyR 的EC50=9 mM。
T13576	β-cyano-L-Alanine Beta-cyano-l-alanine	Others	Others
	β-cyano-L-Alanine (Beta-cyano-l-alanine) 是广泛存在于高等植物中的腈，氰基丙氨酸合成酶以氰化物和半胱氨酸作为底物反应产生。它消除了乙醇对脑缺血/再灌注 (I/R) 损伤的保护作用。