TLR3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

TLR3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 78.7 kDa and the accession number is Q6PCD4.

规格	价格/CNY		数量
100 μg	￥ 5,180	5日内发货
500 μg	￥ 20,700	5日内发货
1 mg	￥ 34,600	5日内发货

规格

价格/CNY

货期

数量

100 μg

￥ 5,180

5日内发货

500 μg

￥ 20,700

5日内发货

1 mg

￥ 34,600

5日内发货

产品描述	TLR3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 78.7 kDa and the accession number is Q6PCD4.

种属	Human
表达系统	HEK293 Cells
标签	C-His
蛋白编号	Q6PCD4
别名	IIAE2, TLR3, CD283
蛋白构建	Ser23-Glu703
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	78.7 kDa (predicted). Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result.

内毒素	< 1 EU/μg by the LAL method.
缓冲液	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
存储	It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	TLR3 is expressed in the central nervous system (CNS), where it is required to control HSV-1, which spreads from the epithelium to the CNS via cranial nerves. TLR3 is also expressed in epithelial and dendritic cells, which apparently use TLR3-independent pathways to prevent further dissemination of HSV-1 and to provide resistance to other pathogens in TLR3-deficient patients. Human TLR3 appears to be redundant in host defense to most microbes but is vital for natural immunity to HSV-1 in the CNS, which suggests that neurotropic viruses have contributed to the evolutionary maintenance of TLR3.