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LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human, Recombinant (His & Avi), Biotinylated

LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human, Recombinant (His & Avi), Biotinylated

产品编号 TMPK-00606
别名: LIR5, HM18, CD85K, ILT-3, LILRB4, ILT3

LILRB4,also known as CD85k and LIR-5, ILT3,  is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 14.77 kDa and the accession number is AAH26309.1.

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LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human, Recombinant (His & Avi), Biotinylated
规格 价格/CNY 货期 数量
100 μg ¥ 6,670 5日内发货
500 μg ¥ 26,700 5日内发货
1 mg ¥ 44,500 5日内发货
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产品目录号及名称: LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human, Recombinant (His & Avi), Biotinylated (TMPK-00606)
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产品描述 LILRB4,also known as CD85k and LIR-5, ILT3,  is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 14.77 kDa and the accession number is AAH26309.1.
种属 Human
表达系统 HEK293 Cells
标签 C-His-Avi
蛋白编号 AAH26309.1
别名 LIR5, HM18, CD85K, ILT-3, LILRB4, ILT3
蛋白构建 Gln22-Lys123
蛋白纯度 > 95% as determined by Tris-Bis PAGE; > 90% as determined by HPLC
分子量 14.77 kDa (predicted). Due to glycosylation, the protein migrates to 15-20 kDa based on Tris-Bis PAGE result.
内毒素 < 1 EU/μg by the LAL method.
缓冲液 Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
存储

It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 LILRB4,also known as CD85k and LIR-5, ILT3,  is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.

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Keywords

LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human, Recombinant (His & Avi), Biotinylated LIR 5 LIR5 ILT 3 HM-18 LILRB 4 HM 18 HM18 LIR-5 CD85K LILRB-4 ILT-3 LILRB4 ILT3 recombinant recombinant-proteins proteins protein

 

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