血小板源生长因子受体

血小板源生长因子受体 (Platelet-Derived Growth Factor Receptors, PDGFRs) 是血小板源生长因子（PDGF）家族成员的细胞表面酪氨酸激酶受体。PDGF亚基-A和-B是调节细胞增殖、细胞分化、细胞生长、发育和包括癌症在内的许多疾病的重要因素。PDGF-R有两种形式，α和β，每种形式由不同的基因编码。根据结合的生长因子，PDGF-R 同源或异源二聚化。对 RTKs 诱导的不同信号级联的检查确立了 Ras/MAPK、PI3K和PLCγ通路作为 PDGFR 信号转导的关键下游介质。此外，活性氧依赖性 STAT3 激活已被确定为血管平滑肌细胞中 PDGFR 信号传导的关键下游介质。

Cat. No.	Product Name / Synonyms	Species	Expression System
TMPY-05789	PDGFRA Protein, Mouse, Recombinant (hFc) PDGFRA Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
PDGFRA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.15 kDa and the accession numbe...
TMPY-06921	PDGFRA Protein, Cynomolgus, Recombinant (His) PDGFRA Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
PDGFRA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.68 kDa and the accession ...
TMPY-01139	PDGFRA Protein, Human, Recombinant (His) PDGFRA Protein, Human, Recombinant (His)	Human	HEK293 Cells
PDGFRA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number...

Cat. No.

Product Name / Synonyms

Species

Expression System

TMPY-05789

PDGFRA Protein, Mouse, Recombinant (hFc)

Mouse

HEK293 Cells

PDGFRA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.15 kDa and the accession numbe...

TMPY-06921

PDGFRA Protein, Cynomolgus, Recombinant (His)

Cynomolgus

HEK293 Cells

PDGFRA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.68 kDa and the accession ...

TMPY-01139

PDGFRA Protein, Human, Recombinant (His)

Human

HEK293 Cells

PDGFRA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number...