Insulin-like 生长因子家族

胰岛素样生长因子 (Insulin-like Growth Factors, IGFs) 是与胰岛素序列相似度高的蛋白质。IGFs是细胞用来与其生理环境进行交流的复杂系统的一部分。这个复杂的系统通常称为 IGF“轴”，由两个细胞表面受体（IGF1R 和 IGF2R）、两个配体（IGF-1 和 IGF-2）、七个高亲和力 IGF 结合蛋白（IGFBP1~IGFBP7）以及相关的 IGFBP 降解酶（统称为蛋白酶）组成。IGF“轴”也称为生长激素/IGF-1 轴。胰岛素样生长因子 1（IGF-1）主要由肝脏分泌，这是生长激素刺激的结果。其中IGF-1 对于正常生理学的调节以及包括癌症在内的许多病理状态的调节都很重要。IGF“轴”已被证明在促进细胞增殖和抑制细胞死亡中发挥作用。

Species：

Expression System：

Tag：

Cat. No.	Product Name / Synonyms	Species	Expression System
TMPY-00837	IGFBP-4 Protein, Mouse, Recombinant (His) IGFBP-4 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
TMPY-00837	IGFBP-4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.2 kDa and the accession numbe...
TMPY-01762	IGF2BP-2 Protein, Human, Recombinant (His & GST) IGF2BP-2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
TMPY-01762	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a member of the IGF-II mRNA-binding protein (IMP) family. IGF2BP2 is a member of a family of mRN...
TMPY-02119	IGFBP-6 Protein, Human, Recombinant (His) IGFBP-6 Protein, Human, Recombinant (His)	Human	HEK293 Cells
TMPY-02119	IGFBP-6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.9 kDa and the accession numbe...
TMPY-02296	IGFBP-7 Protein, Human, Recombinant (aa 1-282, His) IGFBP-7 Protein, Human, Recombinant (aa 1-282, His)	Human	HEK293 Cells
TMPY-02296	IGFBP-7 Protein, Human, Recombinant (aa 1-282, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.9 kDa and the acces...
TMPY-02920	IGFBP-1 Protein, Rhesus, Recombinant (His) IGFBP-1 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293 Cells
TMPY-02920	IGFBP-1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession numb...
TMPY-02969	IGFBP-2 Protein, Rhesus, Recombinant (His) IGFBP-2 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293 Cells
TMPY-02969	IGFBP-2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.8 kDa and the accession numb...
TMPY-03249	IGFBP-4 Protein, Cynomolgus, Recombinant (His) IGFBP-4 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
TMPY-03249	IGFBP-4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa.
TMPY-03251	IGFBP-3 Protein, Cynomolgus, Recombinant (His) IGFBP-3 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
TMPY-03251	IGFBP-3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.1 kDa.
TMPY-04213	IGFBP-2 Protein, Mouse, Recombinant (His) IGFBP-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
TMPY-04213	IGFBP-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number ...
TMPY-04319	IGFBP-2 Protein, Mouse, Recombinant (hFc) IGFBP-2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
TMPY-04319	IGFBP-2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.6 kDa and the accession numbe...
TMPY-04513	IGFBP-6 Protein, Rat, Recombinant (His) IGFBP-6 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
TMPY-04513	IGFBP-6 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.9 kDa and the accession number ...
TMPY-04878	IGF1/IGF-I Protein, Mouse, Recombinant IGF1/IGF-I Protein, Mouse, Recombinant	Mouse	P. pastoris (Yeast)
TMPY-04878	IGF1/IGF-I Protein, Mouse, Recombinant is expressed in yeast. The predicted molecular weight is 7.7 kDa and the accession number is E9PU89.
TMPY-04942	IGF1 LR3 Protein, Human, Recombinant IGF1 LR3 Protein, Human, Recombinant	Human	P. pastoris (Yeast)
TMPY-04942	IGF1 LR3 Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 9.1 kDa and the accession number is P05019-1.
TMPY-06644	IGFBP-7 Protein, Human, Recombinant (hFc & Avi), Biotinylated IGFBP-7 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
TMPY-06644	IGFBP-7 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 54.9...
TMPY-06649	IGFBP-7 Protein, Human, Recombinant (His & Avi), Biotinylated IGFBP-7 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
TMPY-06649	IGFBP-7 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 29.3...
TMPY-06848	IGFBP-7 Protein, Human, Recombinant (K95R, His) IGFBP-7 Protein, Human, Recombinant (K95R, His)	Human	HEK293 Cells
TMPY-06848	IGFBP-7 Protein, Human, Recombinant (K95R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.59 kDa and the accessio...
TMPY-06879	IGFBP-7 Protein, Mouse, Recombinant (aa 26-281, His) IGFBP-7 Protein, Mouse, Recombinant (aa 26-281, His)	Mouse	HEK293 Cells
TMPY-06879	IGFBP-7 Protein, Mouse, Recombinant (aa 26-281, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.69 kDa and the acc...
TMPY-05206	IGFBP-5 Protein, Human, Recombinant (His) IGFBP-5 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
TMPY-05206	IGFBP-5 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 30 kDa and the accession numbe...
TMPY-00835	IGFBP-3 Protein, Human, Recombinant (His) IGFBP-3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
TMPY-00835	IGFBP-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number ...
TMPY-02118	IGFBP-6 Protein, Mouse, Recombinant (His) IGFBP-6 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
TMPY-02118	IGFBP-6 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number ...