B细胞,也称为B淋巴细胞,是淋巴细胞亚型的一种白细胞。它们在适应性免疫系统的体液免疫成分中起作用。在哺乳动物中,B细胞在骨髓中成熟。B 细胞活化发生在次级淋巴器官 (SLO) 中,例如脾脏和淋巴结。B细胞在骨髓中成熟后,它们通过血液迁移到SLO,SLO通过循环淋巴液获得持续的抗原供应。在 SLO 中,当 B 细胞通过其 BCR 与抗原结合时,B 细胞激活开始。
未成熟的 B 细胞可表达 CD19、CD20、CD34、CD38 和 CD45R。大多数成熟 B 细胞表达IgM、CD19、CD20 和 CD22。活化的 B 细胞会表达 CD30。血浆 B 细胞不能表达 CD19,但可表达 CD78。
Cat. No. | Product Name / Synonyms | Species | Expression System |
---|---|---|---|
TMPK-01176 | CD28 Protein, Canine, Recombinant (His)
CD28 Protein, Canine, Recombinant (His)
|
Canine | HEK293 |
CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen present... | |||
TMPK-01177 | CD28 Protein, Canine, Recombinant (mFc)
CD28 Protein, Canine, Recombinant (mFc)
|
Canine | HEK293 |
CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen present... | |||
TMPK-01202 | CD93/C1qR1 Protein, Human, Recombinant (His&Avi), Biotinylated
CD93/C1qR1 Protein, Human, Recombinant (His&Avi), Biotinylated
|
Human | HEK293 |
CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM... | |||
TMPK-01270 | CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
|
Cynomolgus,Rhesus macaque | HEK293 |
The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD11... | |||
TMPK-01278 | CD69 Protein, Cynomolgus, Recombinant (His)
CD69 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 |
CLEC2C (CD69) is a membrane-bound, type II C-lectin receptor and acts as a costimulatory molecule for T cell activation and proliferation. It is involved in lymp... | |||
TMPK-01284 | Syndecan-1 Protein, Cynomolgus, Recombinant (His)
Syndecan-1 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 |
Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteog... | |||
TMPK-01310 | Syndecan-1 Protein, Rabbit, Recombinant (His)
Syndecan-1 Protein, Rabbit, Recombinant (His)
|
Rabbit | HEK293 |
CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix int... | |||
TMPK-01318 | CD24 Protein-VLP, Cynomolgus, Recombinant
CD24 Protein-VLP, Cynomolgus, Recombinant
|
Cynomolgus | HEK293 |
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil pr... | |||
TMPK-01334 | EMMPRIN/CD147 Protein, Canine, Recombinant (His)
EMMPRIN/CD147 Protein, Canine, Recombinant (His)
|
Canine | HEK293 |
CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulati... | |||
TMPY-00002 | CD37 Protein, Mouse, Recombinant (hFc)
CD37 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
CD37 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 43.6 kDa. Accession number: Q4FK35 | |||
TMPY-00004 | CD28 Protein, Rat, Recombinant (hFc)
CD28 Protein, Rat, Recombinant (hFc)
|
Rat | HEK293 |
CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single ... | |||
TMPY-00036 | CD28 Protein, Cynomolgus, Recombinant (hFc)
CD28 Protein, Cynomolgus, Recombinant (hFc)
|
Cynomolgus | HEK293 |
CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single ... | |||
TMPY-00037 | B7-1 Protein, Rat, Recombinant (hFc)
B7-1 Protein, Rat, Recombinant (hFc)
|
Rat | HEK293 |
The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the ... | |||
TMPY-00158 | Siglec-2/CD22 Protein, Rat, Recombinant (hFc)
Siglec-2/CD22 Protein, Rat, Recombinant (hFc)
|
Rat | HEK293 |
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface... | |||
TMPY-00306 | CD93/C1qR1 Protein, Rat, Recombinant (His)
CD93/C1qR1 Protein, Rat, Recombinant (His)
|
Rat | HEK293 |
CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid linea... | |||
TMPY-00349 | Siglec-2/CD22 Protein, Rhesus, Recombinant (His)
Siglec-2/CD22 Protein, Rhesus, Recombinant (His)
|
Rhesus | HEK293 |
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface... | |||
TMPY-00407 | Siglec-2/CD22 Protein, Rat, Recombinant (His)
Siglec-2/CD22 Protein, Rat, Recombinant (His)
|
Rat | HEK293 |
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface... | |||
TMPY-00482 | CD40 Protein, Human, Recombinant (hFc)
CD40 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential r... | |||
TMPY-00618 | BAFF/TNFSF13B Protein, Canine, Recombinant (hFc)
BAFF/TNFSF13B Protein, Canine, Recombinant (hFc)
|
Canine | HEK293 |
B lymphocyte stimulator (BLyS), also known as TNFSF13B, CD257 and BAFF, is a single-pass type II membrane protein, which belongs to the tumor necrosis factor fam... | |||
TMPY-00632 | Fas/CD95 Protein, Cynomolgus, Recombinant
Fas/CD95 Protein, Cynomolgus, Recombinant
|
Cynomolgus | HEK293 |
CD95 (APO-1/Fas) is an important inducer of the extrinsic apoptosis signaling pathway and therapy induced apoptosis of many tumor cells has been linked to the ac... |