E3 Ligase Ligand-Linker Conjugate

Cat. No.	Product Name	CAS No.	Purity
T18872	(S,R,S)-AHPC-PEG5-COOH 化合物 T18872	2172820-14-1	98%
T18872	(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthetic E3 ligase ligand-linker conjugate developed for use in PROTAC technology. It consists of the (S,R,S)-AHPC...
T18824	Thalidomide-O-C6-NH2 TFA 化合物 T18824	1957235-99-2	98%
T18824	Thalidomide-O-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12F36V and BET[1].
T18817	Thalidomide-O-amido-C8-NH2 hydrochloride 化合物 T18817	T18817	98%
T18817	Thalidomide-O-amido-C8-NH2 hydrochloride is a synthetic conjugate of an E3 ligase ligand-linker, which combines a cereblon ligand derived from Thalidomide and a ...
T18812	Thalidomide-PEG2-C2-NH2 TFA 化合物 T18812	2097509-36-7	98%
T18812	Thalidomide-O-amido-PEG3-C2-NH2 TFA, a synthesized E3 ligase ligand-linker conjugate, combines the cereblon ligand based on Thalidomide and a 2-unit PEG linker f...
T18671	(S,R,S)-AHPC-Me-C7 ester 化合物 T18671	T18671	98%
T18671	(S,R,S)-AHPC-Me-C7 ester is a E3 ligase ligand-linker conjugate used to synthesise BCL-XL PROTAC degraders[1].
T18669	(S,R,S)-AHPC-Me-C10-NH2 化合物 T18669	2376139-52-3	98%
T18669	(S,R,S)-AHPC-Me-C10-NH2 is a chemical compound consisting of a synthesized E3 ligase ligand-linker conjugate that incorporates both a VHL ligand and a linker. Th...
T18666	(S,R,S)-AHPC-C4-NH2 化合物 T18666	2138439-53-7	98%
T18666	(S,R,S)-AHPC-C4-NH2 is a custom-synthesized conjugate of an E3 ligase ligand-linker, which combines the VHL ligand based on (S,R,S)-AHPC and a linker specificall...
T18820	Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride 化合物 T18820	2245697-84-9	98%
T18820	Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride is a chemical compound that has been synthesized as an E3 ligase ligand-linker conjugate. This compound incorporate...
T18664	(S,R,S)-AHPC-C3-NH2 化合物 T18664	2361119-88-0	98%
T18664	(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized conjugate consisting of an E3 ligase ligand-linker and the VH032 based VHL ligand, which is commonly used in ...
T18668	(S,R,S)-AHPC-Me-C10-Br 化合物 T18668	T18668	98%
T18668	(S,R,S)-AHPC-Me-C10-Br is a chemically synthesized conjugate that functions as a ligand-linker for E3 ligases. This compound incorporates a VHL E3 ligase linker ...
T18806	Thalidomide-NH-C10-COOH 化合物 T18806	T18806	98%
T18806	Thalidomide-NH-C10-COOH (compound 6b) is a synthetic E3 ligase ligand-linker conjugate. This compound combines the Thalidomide-based von Hippel-Lindau (VHL) liga...
T13671L	(S,R,S)-AHPC-Me dihydrochloride 化合物 T13671L	T13671L	98%
T13671L	(S,R,S)-AHPC-Me dihydrochloride, also known as VHL ligand 2 dihydrochloride, is a chemical compound utilized in the synthesis of ARV-771. ARV-771, a BET PROTAC d...
T18826	Thalidomide-O-PEG2-propargyl 化合物 T18826	2098487-52-4	98%
T18826	Thalidomide-O-PEG2-propargyl (E3 Ligase Ligand-Linker Conjugates 32) is a chemical compound that has been synthesized as a conjugate of an E3 ligase ligand and a...
T7752	(S,R,S)-AHPC-Me 化合物(S,R,S)-AHPC-Me	1948273-02-6	99.86%
T7752	(S,R,S)-AHPC-Me (E3 ligase Ligand 1A) 是基于 (S,R,S)-AHPC 的的 VHL 配体，可用于募集 von Hippel-Lindau (VHL) 蛋白。它可有效降解去势抵抗性前列腺癌细胞中的 BET 蛋白，DC50<1 nM。它可用于合成 ARV-771。
T40002	Pomalidomide-C3-NH2 hydrochloride 化合物Pomalidomide-C3-NH2 hydrochloride	2154342-45-5	99.60%
T40002	Pomalidomide-C3-NH2 hydrochloride 包含基于 Pomalidomide 的 cereblon 配体和 1 个 linker，是合成的 E3 连接酶配体-linker 偶联物，可用于 PROTAC 的合成。
T40001	Pomalidomide-C6-COOH 化合物Pomalidomide-C6-COOH	2225940-50-9	99.57%
T40001	Pomalidomide-C6-COOH 是一种合成的 E3 连接酶配体-接头偶联物，它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 CRBN 配体和接头。
T5102	TGN-020 化合物TGN020	51987-99-6	99.54%
T5102	TGN-020 是一种属于 alkyl chain 类的 PROTAC linker，可用于 PROTAC 的合成分子。TGN020 是一种选择性水通道蛋白 4 (AQP4) 抑制剂，IC50为 3.1 μM。TGN020 减轻大鼠脊髓压迫损伤后的水肿并抑制神经胶质瘢痕的形成。
T40004	Pomalidomide-C7-NH2 hydrochloride 化合物Pomalidomide-C7-NH2 hydrochloride	2093387-55-2	99.36%
T40004	Pomalidomide-C7-NH2 hydrochloride 是一种合成的 E3 连接酶配体-接头偶联物，它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 CRBN 配体和接头。
T40008	Pomalidomide-C6-I TFA 化合物Pomalidomide-C6-I TFA	T40008	99.31%
T40008	Pomalidomide-C6-I TFA 是一种合成的 E3 连接酶配体-接头偶联物，它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 CRBN 配体和接头。
T40003	Thalidomide-NH-C6-NH2 hydrochloride 化合物Pomalidomide-C6-NH2 hydrochloride	2375194-37-7	99.27%
T40003	Thalidomide-NH-C6-NH2 hydrochloride 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker，是合成的 E3 连接酶配体-linker 偶联物，可用于 PROTAC 的合成。