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type I hair keratin fragment [Homo sapiens]/[Ovis aries]/[Rattus norvegicus]

产品编号 TP2188 CAS TP2188

The human type I hair keratin subfamily comprises nine individual members, which can be subdivided into three groups. Group A (hHa1, hHa3-I, hHa3-II, hHa4) and B (hHa7, hHa8) each contains structurally related hair keratins, whereas group C members hHa2, hHa5, and hHa6 represent structurally rather unrelated hair keratins1.

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type I hair keratin fragment [Homo sapiens]/[Ovis aries]/[Rattus norvegicus] Chemical Structure

type I hair keratin fragment [Homo sapiens]/[Ovis aries]/[Rattus norvegicus], CAS TP2188

规格	价格/CNY	货期
1 mg	待询	待询
5 mg	待询	待询
10 mg	待询	待询
25 mg	待询	待询

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生物活性

化学信息

存储 & 溶解度

产品描述	The human type I hair keratin subfamily comprises nine individual members, which can be subdivided into three groups. Group A (hHa1, hHa3-I, hHa3-II, hHa4) and B (hHa7, hHa8) each contains structurally related hair keratins, whereas group C members hHa2, hHa5, and hHa6 represent structurally rather unrelated hair keratins1.
体外活性	Keratins are divided into type I (acidic) and type II (basic to neutral) members, which form the 10-nm intermediate filament cytoskeletal network of epithelial cells through the obligatory association of equimolar amounts of type I and type II keratins [2][3][4].
体内活性	The various type I hair keratin antibodies proved to be highly specific in that they recognized only single protein bands when analyzed in Western blots of one-dimensionally resolved human hair keratins. One exception concerned the hHa2 antibody, which besides the prominent hHa2 protein band also reacted with a slightly larger minor band1. A LEF-1 consensus sequence is invariably located at a highly conserved position in the proximal promoter region of the members of the human type I hair keratin family but it is specifically lacking in the entire promoter of the hHa7 gene5.

分子量	1064.19
分子式	C47H77N13O15
CAS No.	TP2188

存储

keep away from moisture　|　Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度

DMSO: ≥106.4mg/mL

计算器

摩尔浓度计算器

稀释计算器

配液计算器

分子量计算器

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配液浓度

剂量换算

对于不同动物的给药剂量换算，您也可以参考 更多...

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10 只，您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL)，如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法：取 50 μL DMSO 主液，加入 300 μL PEG300，混匀澄清，再加 50 μL Tween 80，混匀澄清，再加 600 μL ddH2O, 混匀澄清。

第一步：请输入动物实验的基本信息

剂量

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动物数量

第二步：请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。

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