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SNAP-25 Protein, Human, Recombinant (His)

SNAP-25 Protein, Human, Recombinant (His)

产品编号 TMPY-02245
别名: synaptosomal-associated protein, 25kDa, SEC9, SNAP, RIC-4, dJ1068F16.2, SNAP-25, bA416N4.2, RIC4

Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the specificity of membrane fusion and to directly execute fusion by forming a tight complex that brings the synaptic vesicle and plasma membranes together. SNAP25 / SUP is a Q-SNARE protein contributing two α-helices in the formation of the exocytotic fusion complex in neurons where it assembles with syntaxin-1 and synaptobrevin. SNAP25 / SUP is involved in the molecular regulation of neurotransmitter release. It may play an important role in the synaptic function of specific neuronal systems. SNAP25 / SUP associates with proteins involved in vesicle docking and membrane fusion. SNAP25 / SUP regulates plasma membrane recycling through its interaction with CENPF. SNAP25 / SUP inhibits P/Q- and L-type voltage-gated calcium channels located presynaptically and interacts with the synaptotagmin C2B domain in Ca2+-independent fashion. In glutamatergic synapses SNAP25 / SUP decreases the Ca2+ responsiveness, while it is naturally absent in GABAergic synapses.

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SNAP-25 Protein, Human, Recombinant (His) Chemical Structure
SNAP-25 Protein, Human, Recombinant (His), CAS N/A
规格 价格/CNY 货期 数量
100 μg ¥ 3,170 现货
200 μg ¥ 5,420 5日内发货
500 μg ¥ 10,990 5日内发货
其他形式的 SNAP-25 Protein, Human, Recombinant (His):
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BCA蛋白浓度测定试剂盒限时半价
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产品目录号及名称: SNAP-25 Protein, Human, Recombinant (His) (TMPY-02245)
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参考文献
产品描述 Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the specificity of membrane fusion and to directly execute fusion by forming a tight complex that brings the synaptic vesicle and plasma membranes together. SNAP25 / SUP is a Q-SNARE protein contributing two α-helices in the formation of the exocytotic fusion complex in neurons where it assembles with syntaxin-1 and synaptobrevin. SNAP25 / SUP is involved in the molecular regulation of neurotransmitter release. It may play an important role in the synaptic function of specific neuronal systems. SNAP25 / SUP associates with proteins involved in vesicle docking and membrane fusion. SNAP25 / SUP regulates plasma membrane recycling through its interaction with CENPF. SNAP25 / SUP inhibits P/Q- and L-type voltage-gated calcium channels located presynaptically and interacts with the synaptotagmin C2B domain in Ca2+-independent fashion. In glutamatergic synapses SNAP25 / SUP decreases the Ca2+ responsiveness, while it is naturally absent in GABAergic synapses.
别名 synaptosomal-associated protein, 25kDa, SEC9, SNAP, RIC-4, dJ1068F16.2, SNAP-25, bA416N4.2, RIC4
分子量 Approxiamtely 24.8 kDa

存储

Lyophilized powder: -20~-80°C for 1 year

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TargetMol Library Books参考文献

1. Hodel A , et al.,1998, Int. J. Biochem. Cell Biol. 30 (10): 1069-73. 2. Sudhof TC, et al.,2002, Nat Rev Neurosci 3 (8): 641-653. 3. Chapman ER et al.,2002, Nat. Rev. Mol. Cell Biol. 3(7): 498-508. 4. Chen X., et al., 2002, Neuron 33:397-409. 5. Huang Q., et al., 2008, FEBS Lett. 582:1431-1436.

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请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。

母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。

体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。

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您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。

Keywords

SNAP-25 Protein, Human, Recombinant (His) synaptosomal-associated protein, 25kDa SEC9 SNAP RIC 4 SEC 9 RIC-4 SEC-9 SNAP 25 dJ1068F16.2 SNAP-25 bA416N4.2 SNAP25 RIC4 Inhibitor inhibitor inhibit

 

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