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Peroxiredoxin 2 Protein, Human, Recombinant (His)

Peroxiredoxin 2 Protein, Human, Recombinant (His)

产品编号 TMPY-02200
别名: PRP, HEL-S-2a, TSA, NKEF-B, TDPX1, PTX1, TPX1, peroxiredoxin 2, PRX2, PRXII, NKEFB

Peroxiredoxin-2, also known as Natural killer cell-enhancing factor B, NKEF-B, Thiol-specific antioxidant protein, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, PRDX2 and NKEFB, is a cytoplasm protein that belongs to the ahpC / TSA family. Peroxiredoxin-2 / PRDX2 contains one thioredoxin domain. Peroxiredoxin-2 / PRDX2 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system. Peroxiredoxin-2 / PRDX2 is not able to receive electrons from glutaredoxin. It may play an important role in eliminating peroxides generated during metabolism. Peroxiredoxin-2 / PRDX2 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. The Peroxiredoxins / Prx are a family of peroxidases that can reduce H2O2 using an electron from thioredoxin (Trx) or other substances. The mammalian Peroxiredoxins / Prx family is divided into six groups (PRDX1,PRDX2, PRDX3, PRDX4, PRDX5, PRDX6) on the basis of homology of amino acid sequences. They are located in the cytosol and play a role in the cell signaling system. All six mammalian peroxiredoxins are expressed in the lung. Peroxiredoxins / Prx is overexpressed in breast cancer tissues to a great extent suggesting that Peroxiredoxins / Prx has a proliferative effect and may be related to cancer development or progression.

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Peroxiredoxin 2 Protein, Human, Recombinant (His) Chemical Structure
Peroxiredoxin 2 Protein, Human, Recombinant (His), CAS N/A
规格 价格/CNY 货期 数量
100 μg ¥ 4,460 5日内发货

Peroxiredoxin 2 Protein, Human, Recombinant (His) 的其他形式现货产品:

C-Reactive Protein Protein, Human, Recombinant Trichostatin A C-Reactive Protein /CRP Protein, Human, Recombinant (His)
产品目录号及名称: Peroxiredoxin 2 Protein, Human, Recombinant (His) (TMPY-02200)
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参考文献
产品描述 Peroxiredoxin-2, also known as Natural killer cell-enhancing factor B, NKEF-B, Thiol-specific antioxidant protein, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, PRDX2 and NKEFB, is a cytoplasm protein that belongs to the ahpC / TSA family. Peroxiredoxin-2 / PRDX2 contains one thioredoxin domain. Peroxiredoxin-2 / PRDX2 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system. Peroxiredoxin-2 / PRDX2 is not able to receive electrons from glutaredoxin. It may play an important role in eliminating peroxides generated during metabolism. Peroxiredoxin-2 / PRDX2 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. The Peroxiredoxins / Prx are a family of peroxidases that can reduce H2O2 using an electron from thioredoxin (Trx) or other substances. The mammalian Peroxiredoxins / Prx family is divided into six groups (PRDX1,PRDX2, PRDX3, PRDX4, PRDX5, PRDX6) on the basis of homology of amino acid sequences. They are located in the cytosol and play a role in the cell signaling system. All six mammalian peroxiredoxins are expressed in the lung. Peroxiredoxins / Prx is overexpressed in breast cancer tissues to a great extent suggesting that Peroxiredoxins / Prx has a proliferative effect and may be related to cancer development or progression.
别名 PRP, HEL-S-2a, TSA, NKEF-B, TDPX1, PTX1, TPX1, peroxiredoxin 2, PRX2, PRXII, NKEFB
分子量 Approxiamtely 24 kDa

存储

Lyophilized powder: -20~-80°C for 1 year

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TargetMol Library Books参考文献

1. Cha M.-K., et al., 1995,  Biochem. Biophys. Res. Commun. 217:900-7. 2. Noh,D.Y. et al., 2001, Anticancer Res. 21 (3B): 2085-90. 3. Chevallet M., et al., 2003, J. Biol. Chem. 278:37146-53. 4. Schremmer,B. et al., 2007, Subcell Biochem. 44 :317-44. 5. Gauci S., et al., 2009, Anal. Chem. 81:4493-501.

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Keywords

Peroxiredoxin 2 Protein, Human, Recombinant (His) TDPX 1 PRP TDPX-1 HEL-S-2a TSA PRX 2 NKEF-B TDPX1 PTX1 PTX 1 TPX-1 PRX-2 TPX1 peroxiredoxin 2 PRX2 PTX-1 PRXII NKEFB TPX 1 Inhibitor inhibitor inhibit

 

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