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LR3-IGF-1 Protein, Mouse, Recombinant (His)

LR3-IGF-1 Protein, Mouse, Recombinant (His)

产品编号 TMPJ-00781   CAS TMPJ-00781
别名: IGF1, insulin-like growth factor 1, Insulin-like growth factor I, somatomedin-C, IGF-1, Somatomedin C

Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. It plays an important role in muscle regeneration and tumor progression. IGF-I binds IGF-I R, IGF-II R, and the insulin receptor. IGF-I association with IGF binding proteins increases its plasma half-life and modulates its interactions with receptors. 在相同实验条件下,摩尔浓度相同的化合物盐形式与游离态具有相同的生物活性,但盐形式 IGF-I 30-41 acetate(82177-09-1 free base) 的水溶性和稳定性通常比游离态更好。

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LR3-IGF-1 Protein, Mouse, Recombinant (His) Chemical Structure
LR3-IGF-1 Protein, Mouse, Recombinant (His), CAS TMPJ-00781
规格 价格/CNY 货期 数量
10 μg ¥ 220 5日内发货
50 μg ¥ 380 5日内发货
500 μg ¥ 3,950 5日内发货
1 mg ¥ 5,530 5日内发货
产品目录号及名称: LR3-IGF-1 Protein, Mouse, Recombinant (His) (TMPJ-00781)
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生物活性
化学信息
存储 & 溶解度
产品描述 Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. It plays an important role in muscle regeneration and tumor progression. IGF-I binds IGF-I R, IGF-II R, and the insulin receptor. IGF-I association with IGF binding proteins increases its plasma half-life and modulates its interactions with receptors.
别名 IGF1, insulin-like growth factor 1, Insulin-like growth factor I, somatomedin-C, IGF-1, Somatomedin C
分子量 12 KDa, reducing conditions
CAS No. TMPJ-00781

存储

Lyophilized powder: -20~-80°C for 1 year

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母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。

体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。

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您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。

Keywords

LR3-IGF-1 Protein, Mouse, Recombinant (His) TMPJ-00781 IGF1 insulin-like growth factor 1 IGF 1 Insulin-like growth factor I somatomedin-C IGF-1 Somatomedin C Inhibitor inhibitor inhibit

 

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