Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Utibapril is an inhibitor of angiotensin-converting enzyme (ACE) with antihypertensive activities.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
25 mg | ¥ 10,600 | 6-8周 | ||
50 mg | ¥ 13,800 | 6-8周 | ||
100 mg | ¥ 17,500 | 6-8周 |
产品描述 | Utibapril is an inhibitor of angiotensin-converting enzyme (ACE) with antihypertensive activities. |
体内活性 | Utibapril significantly inhibits plasma, renal, and vascular ACE but not ventricular ACE activity. vascular ACE activity significantly inhibited by Utibapril (2 μg/kg/day), and Utibapril (250 μg/kg/day) results in a significant inhibition of plasma ACE.After treatment with the higher doses of utibapril, Furthermore, angiotensin I-induced decreases in coronary flow in the isolated heart are significantly inhibited [1]. FPL 63547 is rapidly and extensively excreted as the diacid in the bile but appeared in the urine in negligible amounts[2]. |
别名 | FPL 63547 |
分子量 | 449.56 |
分子式 | C22H31N3O5S |
CAS No. | 109683-61-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Utibapril 109683-61-6 Others FPL63547 FPL-63547 FPL 63547 Inhibitor inhibitor inhibit