keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Substance P TFA (Neurokinin P TFA) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS, targeting the neurokinin 1 receptor (NK1-receptor, NK1R).
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 mg | ¥ 5,898 | 5日内发货 |
Substance P TFA 的其他形式现货产品:
产品描述 | Substance P TFA (Neurokinin P TFA) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS, targeting the neurokinin 1 receptor (NK1-receptor, NK1R). |
体外活性 | The neuropeptide substance P (SP) is mediated by the NK1-R desensitize and resensitize, which may be associated with NK1-R endocytosis and recycling. SP and the NK1-R have internalized into the same clathrin immunoreactive vesicles and then sorted into different compartments. SP is intact at the cell surface and in early endosomes but slowly degraded in perinuclear vesicles. SP induces clathrin-dependent internalization of the NK1-R. The SP/NK1-R complex dissociates in acidified endosomes. SP induces the internalization of the NK1-R both in transfected epithelial cells [1]. |
别名 | Neurokinin P TFA |
分子量 | 1461.67 |
分子式 | C65H99F3N18O15S |
CAS No. | 148470-19-3 |
keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Substance P TFA 148470-19-3 Others Neurokinin P TFA Inhibitor inhibitor inhibit