Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Isogambogic acid shows cytotoxic activiity against KB and drug-resistant KB-V1 cell lines.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
5 mg | ¥ 3,330 | 待询 | ||
1 mL * 10 mM (in DMSO) | ¥ 5,080 | 待询 |
产品描述 | Isogambogic acid shows cytotoxic activiity against KB and drug-resistant KB-V1 cell lines. |
体外活性 | METHODS AND RESULTS: Three xanthone derivatives, gambogic acid, Isogambogic acid and isomorellinol, were isolated from the dried latex of Garcinia hanburyi. Two of them, Isogambogic acid and isomorellinol, are new. Determinations of the structures and stereochemistry were achieved independently by a series of NMR experiments including COSY, ROESY, HMQC, HMBC and selective INEPT. Isolation of isomorellinol from G. hanburyi provided important chemical evidence to link this species to G. morella. The presence of gambogic acid and Isogambogic acid, however, demonstrated the difference between these two species. CONCLUSIONS: Cytotoxic evaluation of these isolates revealed that all three were active against KB and drug-resistant KB-V1 cell lines. |
分子量 | 628.762 |
分子式 | C38H44O8 |
CAS No. | 149655-52-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Isogambogic acid 149655-52-7 Inhibitor inhibitor inhibit