Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Helioxanthin 8-1, an analogue of helioxanthin, exhibits significant in vitro anti-HBV/HCV/HSV-1/HIV activity with EC50 of <5/10/1.4/15 μM.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
25 mg | ¥ 9,620 | 6-8周 | ||
50 mg | ¥ 12,500 | 6-8周 | ||
100 mg | ¥ 17,500 | 6-8周 |
产品描述 | Helioxanthin 8-1, an analogue of helioxanthin, exhibits significant in vitro anti-HBV/HCV/HSV-1/HIV activity with EC50 of >5/10/1.4/15 μM. |
体外活性 | The cyclic hydrazide 28(Helioxanthin 8-1) showed the most potent anti-HBV activity among those helioxanthin analogues tested. In addition, compound 28 exhibited moderately potent activity against HIV. It would therefore be promising to study helioxanthin analogues that contain a six-membered ring instead of the five-membered ring found in the lactam [1]. 8-1 exhibited effective inhibition on DHBV replication. The combination of 8-1 with 3TC resulted in the additional anti-DHBV activity. Viral induced cells displayed higher susceptibility to 8-1 treatment than non-induced cells. HBV X protein might not be an essential factor in the initiation of the biological activity of 8-1, as demonstrated by its absence in DHBV [2]. |
别名 | Helioxanthin analogue 8-1 |
分子量 | 376.32 |
分子式 | C20H12N2O6 |
CAS No. | 840529-13-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (26.57 mM), Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.6573 mL | 13.2866 mL | 26.5731 mL | 66.4328 mL |
5 mM | 0.5315 mL | 2.6573 mL | 5.3146 mL | 13.2866 mL | |
10 mM | 0.2657 mL | 1.3287 mL | 2.6573 mL | 6.6433 mL | |
20 mM | 0.1329 mL | 0.6643 mL | 1.3287 mL | 3.3216 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Helioxanthin 8-1 840529-13-7 Others Helioxanthin 8 1 Helioxanthin analogue 8-1 Helioxanthin 81 Inhibitor inhibitor inhibit