Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Calcitetrol is the hormonally active form of vitamin D with three hydroxyl groups.
产品描述 | Calcitetrol is the hormonally active form of vitamin D with three hydroxyl groups. |
体内活性 | Calcitriol increases blood calcium levels ([Ca2+]) by promoting absorption of dietary calcium from the gastrointestinal tract and increasing renal tubular reabsorption of calcium, thus reducing the loss of calcium in the urine. Calcitriol also stimulates the release of calcium from bone by its action on the specific type of bone cells referred to as osteoblasts, causing them to release RANKL, which in turn activates osteoclasts. |
别名 | 1α, 24, 25-Trihydroxy VD3 |
分子量 | 432.64 |
分子式 | C27H44O4 |
CAS No. | 72203-93-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Calcitetrol 72203-93-1 Others 1a, 24, 25-Trihydroxy VD3 1alpha, 24, 25-Trihydroxy VD3 1α, 24, 25-Trihydroxy VD3 Inhibitor inhibitor inhibit