Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CS476 is a potent drug of hypoglycaemic.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
25 mg | ¥ 10,600 | 6-8周 | ||
50 mg | ¥ 13,800 | 6-8周 | ||
100 mg | ¥ 17,500 | 6-8周 |
产品描述 | CS476 is a potent drug of hypoglycaemic. |
体内活性 | CS476 has no hypoglycaemic effect in totally pancreatectomized dogs nor in streptozotocin diabetic dogs and rats. The maximal hypoglycaemia produced by intravenous administration of CS476 is comparable on a weight basis to that produced by Glibenclamide, in normal fasting dogs, rabbits, rats and mice. Randomized Latin square experiments in dogs show that CS476(0.03 mg/kg; p.o. ) and of Glibenclamide cause the same maximal decrease of blood glucose and that CS476 has the shorter duration of action. The insulin releasing activity is studied in dogs after intravenous and oral administration of equipotent doses of CS476, Tolbutamide and Glibenclamide[1]. |
别名 | NSC302998 |
分子量 | 471.57 |
分子式 | C24H29N3O5S |
CAS No. | 41177-35-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
CS476 41177-35-9 Others NSC-302998 NSC302998 CS 476 NSC 302998 CS-476 Inhibitor inhibitor inhibit