Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CPPG is a potent antagonist of group II/III mGlu receptors. CPPG exhibits some selectivity (approximately 20 fold) for group III (IC50: 2.2 nM) over group II (IC50: 46.2 nM) mGlu receptors in the rat cerebral cortex.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 647 | 35日内发货 | ||
5 mg | ¥ 1,890 | 35日内发货 | ||
10 mg | ¥ 3,410 | 35日内发货 | ||
25 mg | ¥ 7,730 | 35日内发货 |
产品描述 | CPPG is a potent antagonist of group II/III mGlu receptors. CPPG exhibits some selectivity (approximately 20 fold) for group III (IC50: 2.2 nM) over group II (IC50: 46.2 nM) mGlu receptors in the rat cerebral cortex. |
靶点活性 | mGlu receptor (Group II):46.2 nM (IC50), mGlu receptor (Group III):2.2 nM (IC50) |
体外活性 | CPPG ((RS)-CPPG) potently reversed both L-AP4 (IC50: 2.2 nM)- and L-CCG-I (IC50: 46.2 nM) -mediated inhibition of forskolin-stimulated cyclic AMP accumulation in adult rat cortical slices. CPPG has weak effects at the group I mGlu receptors in both the neonatal rat cortex and cultured cerebellar granule cells. |
别名 | (RS)-CPPG |
分子量 | 271.21 |
分子式 | C11H14NO5P |
CAS No. | 183364-82-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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CPPG 183364-82-1 Others (RS)-CPPG Inhibitor inhibitor inhibit