Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Arterolane is an antimalarial compound. For against P. falciparum Ro73 and W2, the IC50s are both 1.1 nM.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
2 mg | ¥ 1,950 | 5日内发货 | ||
5 mg | ¥ 2,890 | 5日内发货 | ||
25 mg | ¥ 10,500 | 10-14周 | ||
50 mg | ¥ 13,700 | 10-14周 | ||
100 mg | ¥ 22,100 | 10-14周 | ||
1 mL * 10 mM (in DMSO) | ¥ 3,180 | 5日内发货 |
产品描述 | Arterolane is an antimalarial compound. For against P. falciparum Ro73 and W2, the IC50s are both 1.1 nM. |
靶点活性 | P. falciparum (W2):1.1 nM, P. falciparum (Ro73):1.1 nM |
体外活性 | Arterolane also shows inhibitory activity against several other P. falciparums, with IC50s of 1.0, 1.6, 0.90, 0.91, 1.4, 1.5, 0.83, and 0.84 ng/mL for P. falciparum K1, Fc27, FVO, NF54, HB3, FCB1, ITG2-F6, and MAD20, respectively[1]. Arterolane (Trioxolane 7; OZ277; RBx-11160) is an antimalarial agent, with IC50s of both 1.1 nM (0.43 ng/mL) against P. falciparum Ro73 and W2, respectively. |
别名 | OZ 277, 青蒿氧烷, RBx 11160 |
分子量 | 392.53 |
分子式 | C22H36N2O4 |
CAS No. | 664338-39-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (254.76 mM), Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.5476 mL | 12.7379 mL | 25.4758 mL | 63.6894 mL |
5 mM | 0.5095 mL | 2.5476 mL | 5.0952 mL | 12.7379 mL | |
10 mM | 0.2548 mL | 1.2738 mL | 2.5476 mL | 6.3689 mL | |
20 mM | 0.1274 mL | 0.6369 mL | 1.2738 mL | 3.1845 mL | |
50 mM | 0.051 mL | 0.2548 mL | 0.5095 mL | 1.2738 mL | |
100 mM | 0.0255 mL | 0.1274 mL | 0.2548 mL | 0.6369 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Arterolane 664338-39-0 Others OZ-277 OZ 277 青蒿氧烷 OZ277 RBx 11160 Inhibitor inhibitor inhibit