Cat. No. | Product Name | Target | Signaling Pathways |
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TP1004L |
Beta-MSH (1-22) (human) acetate
Beta-MSH (1-22) (human) acetate (17908-57-5 Free base),醋酸Β-促黑激素(人) |
Melanocortin Receptor | GPCR/G Protein; Neuroscience |
Beta-MSH (1-22) (human) acetate (Beta-MSH (1-22) (human) acetate (17908-57-5 Free base)) 是一种 22 肽,是一种内源性黑皮质素 4 受体 (MC4-R) 激动剂。 | |||
TP1004 |
β-Melanocyte Stimulating Hormone (MSH), human
Beta-MSH (1-22) (human) |
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Stimulating -Melanocyte Stimulating Hormone (MSH), human TFA, is a 22 peptide and is an endogenous melanocortin-4 receptor.MC4 - R) agonists. | |||
TP2212L |
a-MSH, amide Acetate(581-05-5 free base)
|
Melanocortin Receptor | GPCR/G Protein; Neuroscience |
a-MSH, amide Acetate(581-05-5 free base) 是一种内源性黑皮质素受体 4 (MC4R) 激动剂,具有抗炎和解热活性。 α-MSH 是阿片黑皮质素原 (POMC) 的翻译后衍生物。 | |||
TP1003 |
Beta-MSH (1-22) human TFA (17908-57-5 free base)
Beta-MSH (1-22) human TFA,β-Melanocyte Stimulating Hormone (MSH), human TFA |
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β-Melanocyte Stimulating Hormone (MSH), human (Synonyms: Beta-MSH (1-22) (human)) β-Melanocyte Stimulating Hormone (MSH), human, a 22-residue peptide, acts as an endogenous melanocortin-4 receptor (MC4-R) agonist. | |||
TP1893L1 |
[D-Trp8]-γ-MSH acetate(321351-81-9 free base)
|
Melanocortin Receptor | GPCR/G Protein; Neuroscience |
[D-Trp8]-γ-MSH acetate(321351-81-9 free base) 是选择性黑皮质素 3 (MC3) 受体激动剂(对人 MC3、MC5 和 MC4 受体的 IC50 值分别为 6.7、340 和 600 nM)。显示有抗炎功效。 | |||
TP1002L |
γ-1-MSH, amide acetate (72629-65-3 free base)
γ-1-MSH, amide acetate |
Others | Others |
γ-1-MSH, amide acetate (72629-65-3 free base) 是 ACTH/β-内啡肽 (β-EP) 前体蛋白 N 末端区域的一种推定激素,RIA 使用抗 γ-3-MSH 抗血清对产生 ACTH 的小鼠进行了研究垂体肿瘤细胞,AtT-20/D16v。 | |||
T75965 |
β-Melanocyte Stimulating Hormone (MSH), human TFA
|
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β-Melanocyte Stimulating Hormone (MSH), human TFA,为一种具有22个氨基酸残基的肽类化合物,是内源性黑皮质素-4 受体(melanocortin-4 receptor; MC4-R)的激动剂。 | |||
T76340 |
(Nle4)-α-MSH
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(Nle4)-α-MSH 是一种黑素细胞刺激激素α-MSH 的合成类似物。(Nle4)-α-MSH 能够使青蛙皮肤可逆变黑,并在热碱处理后表现出延长的活性。 | |||
T75851 |
γ1-MSH TFA
|
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γ1-MSH TFA 是黑素皮质素 MC3受体激动剂,对大鼠 MC3受体的 Ki 为 34 nM。γ1-MSH TFA 在 MC4 (Ki=1318 nM) 上表现出约 40 倍的选择性。 | |||
T80687 |
γ3-MSH
|
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γ3-MSH 源于 pro-opiomelanocortin (POMC) 的 N 端,能够激活人肾上腺肿瘤细胞分泌醛固酮。 | |||
T76346 |
(D-Phe7)-α-MSH
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(D-Phe7)-α-MSH 是一种 α-MSH 类似物。 | |||
T35406 |
α-MSH TFA
|
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α-Melanocyte-stimulating hormone (α-MSH) is a 13-amino acid peptide hormone produced by post-translational processing of proopiomelanocortin (POMC) in the pituitary gland, as well as in keratinocytes, astrocytes, monocytes, and gastrointestinal cells.1It is an agonist of melanocortin receptor 3 (MC3R) and MC4R that induces cAMP production in Hepa cells expressing the human receptors (EC50s = 0.16 and 56 nM, respectively).2α-MSH (100 pM) reducesS. aureuscolony formation andC. albicansgerm tube fo... | |||
T83188 |
Acetyl-α-MSH (11-13)
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Acetyl-α-MSH (11-13)为α-MSH C端三肽的乙酰化形式,展现解热及抗炎特性。 | |||
T75854 |
[D-Trp8]-γ-MSH TFA
|
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[D-Trp8]-γ-MSH TFA 是一种有效的、选择性的黑皮质素3 (MC3)受体激动剂,在 CHO 细胞中,抑制 hMC3,hMC4和 hMC5的 IC50值分别为 6.7 nM,600 nM 和 340 nM。[D-Trp8]-γ-MSH TFA 显示出对多种炎症性疾病(如类风湿关节炎和结肠炎)的保护作用。 | |||
T75849 |
Lys-γ3-MSH(human) TFA
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Lys-γ3-MSH(human) TFA是源自POMC片段C端的黑素皮质素肽,具备增强大鼠肾上腺对促肾上腺皮质激素(ACTH)的类固醇生成反应的能力。该化合物作为一种有效的脂解激活剂,其表观EC50值为3.56 nM,能够激活激素敏感脂肪酶(HSL)和紫苏脂素A,进而促进脂解。 | |||
T75971 |
γ-1-Melanocyte Stimulating Hormone (MSH), amide
|
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γ-1-Melanocyte Stimulating Hormone (MSH), amide为含11个氨基酸的多肽,主要通过激活黑皮质素受体3 (MC3-R) 调节钠 (Na+) 平衡及血压。 | |||
T76347 |
Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
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Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2 是一种促黑素激素,能够激活黑素细胞。该化合物具有促进酪氨酸酶活性的功能,并在大鼠模型中显示出调节体温的效果。 | |||
TP2212 |
a-MSH, amide
|
Others | Others |
a-MSH, amide is a peptide with the sequence Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2, MW= 1664.9. The melanocyte-stimulating hormones (collectively referred to as MSH or intermedins) are a class of peptide hormones that are produced by c | |||
T35460 |
β-Endorphin (rat)
|
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β-Endorphin (β-EP) is an endogenous opioid neuropeptide with diverse biological activities. It is produced via piomelanocortin cleavage in the pituitary gland, hypothalamus, and in lymphocytes, then migrates to its sites of action which include plasma, gut, skin, placenta, cerebrospinal fluid, and cardiac tissues. β-EP induces concentration-dependent decreases in electrically stimulated contraction of the mouse vas deferens that can be reversed by the μ-opioid antagonist CTP and δ-opioid antagon... |