Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0827 |
Cefsulodin sodium
Cefsulodine sodium,Sulcephalosporin,头孢磺啶钠 |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefsulodin sodium (Sulcephalosporin) 是β内酰胺抗生素,对缘脓杆菌和肠杆菌有活性。 | |||
T12231 |
NITD-349
|
Others; Antibacterial | Microbiology/Virology; Others |
NITD-349 是MmpL3的抑制剂,它对毒性结核分枝杆菌 H37Rv 显示出高效的抗分枝杆菌活性,MIC50 为 23 nM。 | |||
T61067 | MurB-IN-1 | ||
MurB-IN-1 (compound 44) is a potent inhibitor of MurB, an essential enzyme involved in the synthesis of bacterial cell wall. With a binding affinity of K d 3.57 μM, MurB-IN-1 effectively hinders the activity of MurB, presenting a promising therapeutic option against P. aeruginosa, a highly virulent and opportunistic pathogen associated with severe infections and mortality [1]. | |||
T81360 |
PSMα3 TFA
|
||
PSMα3 TFA 作为一种肽类化合物,主要用于诱导生成耐受性的树突细胞(DC),以应用于DC疫苗接种。该化合物能对TLR2和TLR4诱导的DC成熟过程进行调节,抑制促炎和消炎细胞因子的产生,降低抗原摄取,并影响人单核细胞来源DC的渗透和调节能力。此外,PSMα3 TFA 是耐甲氧西林金黄色葡萄球菌(MRSA)中最有毒株释放的关键毒素之一。 |