Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T60014 |
SHEN26
|
Antiviral | Immunology/Inflammation |
SHEN26 具有抗病毒活性,可用于治疗病毒感染的研究。 | |||
T60540 |
Netivudine
|
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Netivudine 是一种有效的核苷类逆转录酶抑制剂(NRTIs),是一种核苷类似物,具有抗水痘带状疱疹病毒活性,可用于治疗人类免疫缺陷病毒(HIV)感染。Netivudine 通过抑制逆转录酶起作用,通过抑制作用减少体内的病毒载量,减缓疾病的进展。 | |||
T61824 |
NIOCH 14
|
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NIOCH 14 is an antiviral agent and pro-drug with demonstrated potency against orthopoxviruses. It exhibits significant efficacy in reducing infection rates and lung viral load in mice. NIOCH 14 is particularly useful for anti-smallpox research [1] [2], as it displays marked anti-orthopoxvirus activity. | |||
T76846 | Casirivimab | ||
Casirivimab (REGN10933) 是一种人的单克隆抗体,靶向导致 COVID-19 的SARS-CoV-2病毒。Casirivimab 对 COVID-19 变种缺乏疗效。Casirivimab 可与Imdevimab 联合使用,有效降低病毒载量,改善病症。 | |||
T76847 | Imdevimab | ||
Imdevimab (REGN10987) 是一种人的单克隆抗体,靶向导致 COVID-19 的SARS-CoV-2病毒。Imdevimab 对 COVID-19 变种缺乏疗效。Imdevimab 可与Casirivimab 联合使用,有效降低病毒载量,改善病症。 | |||
T82937 |
ATV041
|
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ATV041是一种结合了布洛芬和核苷酸类似物的口服活性化合物。该化合物优化了口服药物动力学(PK)特性和组织分布,显示出对抗小鼠肝炎病毒(MHV)的能力。ATV041能够剂量依赖性地降低病毒载量,减少组织损伤并减轻病毒引发的炎症。 | |||
T69731 |
Remdesivir maleate
|
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Remdesivir, also known as GS-5734, is a prodrug form of the antiviral nucleoside analog GS-44152. Remdesivir is a broad spectrum anti-viral drug that has shown to inhibit SARS-CoV-2, in vitro and in vivo. Efficacy of remdesivir against Ebola virus has been demonstrated. Remdesivir inhibits SARS-CoV-2 replication, reduces viral load, and exerts protective effects in SARS-CoV-2 infected animals. Remdesivir also reduces the pathological process, alleviates mild symptoms, and improves pulmonary les... | |||
T76991 | Suvizumab | ||
Suvizumab (KD-247) 是一种抗HIV-1的中和抗体。Suvizumab 有效中和了HIV-1MN、HIV-1SF2和HIV-189.6,IC50值分别为 0.1 µg/mL、1.0 µg/mL 和 0.2 µg/mL。Suvizumab 减少了HIV 的病毒载量。Suvizumab 具有良好的耐受性,可用于预防HIV 感染。 | |||
T83707 |
F9170 TFA
|
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F9170是一种抗病毒肽,对应HIV-1包膜糖蛋白的789-803氨基酸。它与HIV-1包膜蛋白胞浆尾部的LLP1域结合,并抑制HIV-1 IIIB对MT-2细胞的感染(EC50 = 0.19 µM)。在恒河猴模型的类人猿免疫缺陷病毒(SHIV)感染中,F9170 (3 mg/kg)能降低血浆病毒负荷。 | |||
T37295 |
Ganglioside GM1 Asialo Mixture
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Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 by neuraminidase. Ganglioside GM1 asialo is a glycolipid receptor for P. aeruginosa flagellin and stimulates defensive responses in host cells, including extracellular ATP release, calcium mobilization, and ERK1/2 phosphorylation when stimulated by flagellin and an anti-ganglioside GM1 asialo antibody. The percentage of ganglioside GM1 asialo-positive na... |