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Cat. No. Product Name Target Signaling Pathways
T37772 tetranor-12(R)-HETE

Others Others
Metabolism of 12(R)-HETE in corneal tissue produces predominantly the compound resulting from the loss of four carbon atoms through β-oxidation from C-1. This metabolite is 8(R)-hydroxy hexadecatrienoic acid (8(R)-HHxTrE) or 2,3,4,5-tetranor 12(R)-HETE.
T37631 tetranor-12(S)-HETE

Others Others
12(S)-HETE is a product of arachidonic acid metabolism through the 12-lipoxygenase pathway. It is primarily found in platelets, leukocytes, and to a lesser extent in smooth muscle cells. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix. tetranor-12(S)-HETE is the major β-oxidation product resulting from peroxisomal metabolism of 12(S)-HETE in numerous tissues, and Lewis lung carcinoma cells. No biological function has yet been determined for tetran...

化合物

tetranor-12(R)-HETE
Cat.No: T37772
Synonym:
Target: Others
tetranor-12(S)-HETE
Cat.No: T37631
Synonym:
Target: Others
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