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Search Results for " sphingomyelin synthase "

5

抑制剂 & 化合物

1

天然产物

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Cat. No. Product Name Target Signaling Pathways
T15044 D609

Apoptosis; Antioxidant Apoptosis; oxidation-reduction
D609 (Tricyclodecan-9-yl-Xanthogenate) 具有广泛的生物活性,包括抗氧化、抗凋亡、抗胆碱能、抗肿瘤、抗炎、抗病毒、抗增殖和神经保护活性。D609 通过引起磷脂酰胆碱 (PC) 特异性磷脂酶 C (PC-PLC) 和鞘磷脂合酶 (SMS) 的竞争性抑制来发挥作用。
T15822 Ly93

Others Others
Ly93 是一种具有选择性和口服活性的鞘磷脂合成酶 2(SMS2)抑制剂(IC50:91 nM),可用于研究动脉粥样硬化。
T12937 SMS1-IN-1

Others Others
SMS1-IN-1 是一种有效的鞘磷脂合成酶1 (SMS1, IC50 = 2.1 μM) 抑制剂,可用于动脉粥样硬化研究。
T7263 SMS2-IN-2

SMS2 inhibitors

Others Others
SMS2-IN-2 (SMS2 inhibitors) 是一种具有高度选择性、口服具有活力的鞘磷脂合成酶 2 抑制剂,能够作用于 SMS2 (IC50:100 nM)和 SMS1 (IC50:56 nM)。它可减轻慢性炎症反应。
T36188 Ceramide Phosphoethanolamines (bovine)

Ceramide phosphoethanolamine (CPE) is an analog of sphingomyelin that contains ethanolamine rather than choline as the head group. It is the principal membrane phospholipid in invertebrates such as Drosophila, which lacks sphingomyelin. It is only produced in small amounts in mammalian cells, accounting for approximately 0.02 mol% of total phospholipids in mouse testis and brain. In Drosophila, CPE is biosynthesized by CPE synthase from ceramide and cytidine diphosphate-ethanolamine in the Golgi...

化合物

D609
Cat.No: T15044
Synonym:
Target: Apoptosis, Antioxidant
Ly93
Cat.No: T15822
Synonym:
Target: Others
SMS1-IN-1
Cat.No: T12937
Synonym:
Target: Others
SMS2-IN-2
Cat.No: T7263
Synonym: SMS2 inhibitors
Target: Others
Ceramide Phosphoethanolamines (bovine)
Cat.No: T36188
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN6772 Malabaricone C

Others Others
Malabaricone C 是天然的鞘磷脂合成酶抑制剂,对 SMS 1 和 SMS 2 的IC50分别为 3 和 1.5 μM。

天然产物

Malabaricone C
Cat.No: TN6772
Synonym:
Target: Others
TargetMol Loading
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