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抑制剂 & 化合物

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T5851	N-Methylpyrrolidone N-甲基吡咯烷酮,1-Methyl-2-pyrrolidinone	Others	Others
	N-Methylpyrrolidone (1-Methyl-2-pyrrolidinone) 是一种有机极性溶剂，是一种五元环酰胺，普遍用于粘合剂，油漆，燃料和药品的生产。
T40475	Ceftobiprole medocaril BAL5788,头孢比普酯	Antibacterial	Microbiology/Virology
	Ceftobiprole medocaril (BAL5788) 是 Ceftobiprole 的前药。Ceftobiprole 是一种广谱的头孢菌素，对耐甲氧西林金黄色葡萄球菌具有活性。
TQ0077	Ceftobiprole Ro 63-9141,BAL 9141,头孢吡普	Antibacterial	Microbiology/Virology
	Ceftobiprole (Ro 63-9141) 是一种广谱头孢菌素，对甲氧西林耐受的金黄色葡萄球菌的MIC90值为 2 μg/mL。
T2239L	Raltegravir 雷特格韦,MK-0518	HIV Protease; Integrase	Microbiology/Virology; Proteases/Proteasome
	Raltegravir (MK-0518) 是一种HIV 整合酶抑制剂。
T71207	(R)-(+)-Blebbistatin O-Benzoate
	(R)-(+)-Blebbistatin O-Benzoate is a derivative of Blebbistatin. (R)-(+)-Blebbistatin is a 1-phenyl-2-pyrrolidinone derivative and a selective inhibitor of non-muscle myosin II. It blocks cell blebbing rapidly and reversibly and also disrupts directed cell migration and cytokinesis in vertebrate cell. (R)-(+)-Blebbistatin can also inhibit contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. (R)-(+)-Blebbistatin is suitable as a negative control for (S)-(-)-...
T72141	Ceftobiprole medocaril sodium 头孢比普酯钠盐,BAL5788 sodium
	Ceftobiprole medocaril (BAL5788) sodium 是 Ceftobiprole 的胃肠外前药。Ceftobiprole 是一种非肠道吡咯烷酮头孢菌素。Ceftobiprole 是一种广谱头孢菌素，对甲氧西林 (MRSA) 和耐万古霉素葡萄球菌 (VRSA) 和耐青霉素链球菌具有高水平的体外活性。Ceftobiprole 也抑制革兰氏阳性和革兰氏阴性病原体。
T37441	KMN-80
	The prostaglandin E receptor 4 (EP4) is one of four G protein-coupled receptors that mediate the actions of prostaglandin E2 . Binding of PGE2 to the EP4 receptor causes an increase in intracellular cyclic AMP, which plays important roles in bone formation and resorption, cancer, and atherosclerosis. KMN-80 is a substituted γ-lactam (pyrrolidinone) derivative of PGE1 that acts as a selective and potent agonist of EP4 with an IC50 value of 3 nM (IC50 = 1.4 μM for EP3 and > 10 μM for all other pro...

化合物

N-Methylpyrrolidone

Cat.No: T5851

Synonym: N-甲基吡咯烷酮,1-Methyl-2-pyrrolidinone

Target: Others

Ceftobiprole medocaril

Cat.No: T40475

Synonym: BAL5788,头孢比普酯

Target: Antibacterial

Ceftobiprole

Cat.No: TQ0077

Synonym: Ro 63-9141,BAL 9141,头孢吡普

Target: Antibacterial

Raltegravir

Cat.No: T2239L

Synonym: 雷特格韦,MK-0518

Target: HIV Protease, Integrase

(R)-(+)-Blebbistatin O-Benzoate

Cat.No: T71207

Synonym:

Target:

Ceftobiprole medocaril sodium

Cat.No: T72141

Synonym: 头孢比普酯钠盐,BAL5788 sodium

Cat. No.	Product Name	Target	Signaling Pathways
TN3117	5-Hydroxy-2-pyrrolidinone	Others	Others
	5-Hydroxy-2-pyrrolidinone是一种天然产物，属于马钱科醉鱼草属，其产品编号为 TN3117，CAS号为 62312-55-4。5-Hydroxy-2-pyrrolidinone可用作对照参考。