Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8873 |
Bractoppin
|
Others; DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others |
Bractoppin 是一种BRCA1 (t)BRCT domain 识别磷酸肽的选择性抑制剂,IC50为 74 nM。它优先抑制 BRCA1 -tBRCT 依赖的 DNA 损伤。它减少 BRCA1 对 DNA 断裂片段的招募,进而抑制损伤诱导的 G2 期阻滞和重组酶 RAD51 的组装。 | |||
TP2211 |
2B-(SP)
|
Others | Others |
Selective phosphopeptide substrate for glycogen synthase kinase-3 (GSK-3) | |||
T41019 |
Histone H1-derived Peptide
Histone H1-derived Peptide |
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Histone H1-derived peptide is a phosphopeptide with peptide substrates that consist of a sequence aligned with the optimal recognition motif for cyclin-dependent kinases (CDKs). | |||
T40219 |
CGP78850
|
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CGP78850 is a potent and selective Grb2 SH2-phosphopeptide interaction antagonist that holds potential for cancer research. | |||
TP2084 |
N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide
|
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Phosphopeptide; binds to the src SH2 domain. | |||
TP2085 |
Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH
N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu |
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Phosphopeptide ligand for the src SH2 domain (IC50 = 1 μM). Blocks src interactions with EGFR and FAK. | |||
T38965 |
EPQpYEEIPIYL
|
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EPQpYEEIPIYL, a phosphopeptide, is a ligand for the Src homology 2 (SH2) domain. It activates members of the Src family, such as Lck, Hck, and Fyn, through the binding interaction with SH2 domains. | |||
TP2053 |
Caffeic acid-pYEEIE
|
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Phosphopeptide ligand for the src SH2 domain (IC50 = 42 nM); displays 30-fold higher affinity than N-acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu (Ac-pYEEIE,). | |||
T75929 |
Caffeic acid-pYEEIE TFA
|
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Caffeic acid-pYEEIE TFA 是一种非磷酸肽抑制剂,对 GST-Lck-SH2 结构域具有强大的结合亲和力。 |