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Cat. No. | Product Name | Target | Signaling Pathways |
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T37248 |
Pantothenate Kinase Inhibitor
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Pantothenate Kinase Inhibitor (PANKi) is a reversible inhibitor of pantothenate kinase (PanK; IC50s = 70, 92, and 25 nM for PanK1β, PanK2, and PanK3, respectively), the rate-limiting enzyme in the synthesis of coenzyme A .1It binds to the ATP-PanK3 complex with an apparent binding constant of 300 nM and exhibits mixed-type inhibition with respect to ATP and pantothenate. PANKi inhibits CoA biosynthesis in C3A cells (IC50= 0.9 μM) with no effect on cell viability when used at concentrations up to... | |||
T3602 |
D-Pantothenic acid sodium
泛酸钠,D-Pantothenate Sodium,D-Pantothenic acid sodium salt,Sodium pantothenate,D-泛酸钠,vitamin B5 sodium |
Apoptosis; Others | Apoptosis; Others |
D-Pantothenic acid sodium (vitamin B5 sodium) 是一种必需的微量营养素,作为辅酶 A 的前体,在调节碳水化合物,脂质,蛋白和核酸代谢中发挥关键作用。 | |||
T29875 |
Allantoin calcium pantothenate
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Allantoin calcium pantothenate is a protein aggregate suppressor. | |||
T61374 |
Pantothenate kinase-IN-1
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Pantothenate kinase-IN-1 (Compound 1) 是一种泛酸激酶 (pantothenate kinase (PANK)) 调节剂,对 PANK3的 IC50值为 0.51 μM。Pantothenate kinase-IN-1 具有合理的配体效率 (LipE = 2.8) | |||
T64341 |
H-β-Ala-AMC TFA
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Others | Others |
H-β-Ala-AMC TFA 是氨基肽酶的底物之一。 | |||
T5185 |
PZ-2891
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Others | Others |
PZ-2891 是可口服,能渗透血脑屏障的泛酸激酶调节剂。它抑制人泛酸激酶 PANK1β,PANK2 和 PANK3,IC50分别为 40.2 nM,0.7 nM 和 1.3 nM。它在高浓度下充当正构抑制剂,在较低亚饱和浓度下充当变构激活剂。 | |||
T27350 |
Fosmetpantotenate
RE-024,RE024,RE 024 |
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Fosmetpantotenate, a immunomodulator, is used for treatment of Pantothenate Kinase Associated Neurodegeneration (PKAN). |
Cat. No. | Product Name | Target | Signaling Pathways |
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T6480 |
D-Pantothenic acid
vitamin B5,pantothenate,D-泛酸 |
Others | Others |
D-Pantothenic acid (vitamin B5) 是必需的微量营养素,是辅酶 A 的前体,在很多生物过程中发挥关键作用,如调节碳水化合物,脂质,蛋白和核酸代谢。 | |||
T3551 |
D-Pantothenic acid hemicalcium salt
泛酸钙,D-Pantothenic Acid Calcium,D-泛酸半钙,Calpanate,Calcium D-pantothenate,Vitamin B5 calcium salt,Calcium pantothenate,Calcium D-Panthotenate |
Apoptosis; Endogenous Metabolite | Apoptosis; Metabolism |
D-Pantothenic acid hemicalcium salt (Calcium pantothenate) 是一种水溶性维生素,能够减少苹果汁中的棒曲霉素。 | |||
T83582 |
(±)-Pantothenic acid
(±)-Vitamin B5,(±)-Pantothenate |
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(±)-Pantothenic acid ((±)-Pantothenate) 作为 B 组维生素的一员,对于哺乳动物细胞中辅酶 A (CoA) 的生物合成是不可或缺的。此外,该化合物能防护丙戊酸 (VPA) 在 CD-1 小鼠中引起的神经管缺陷 (NTD)。 | |||
T1390 |
DL-Panthenol
Panthenol,DL-泛醇,DL-Pantothenyl alcohol,DL-Pantothenol |
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DL-Panthenol (DL-Pantothenyl alcohol) 是一种泛酸的醇类衍生物。它广泛应用于皮肤和毛发护理研究。它具有睫毛保护作用。 | |||
T10857 |
Coenzyme A
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Endogenous Metabolite | Metabolism |
Coenzyme A 是所有活细胞中必需的辅助因子,由泛酸,三磷酸腺苷和半胱氨酸合成的。Coenzyme A 与过氧化物酶 5 共价结合导致其过氧化物酶活性完全抑制,通过 DTT 还原能够逆转。Coenzyme A 及其硫酯衍生物是主要分解代谢,合成代谢途径和基因表达调控的关键参与者。 | |||
T0978 |
Pantethine
LBF disulfide,Pantosin,Pantetina,Bis-pantethine,泛硫乙胺(维生素B5),泛硫乙胺,Pantomin,D-Pantethine |
Endogenous Metabolite | Metabolism |
D-Pantethine (Pantomin) 是泛酸的二聚体形式, 是生产辅酶 A 的中间体。D-Pantethine 能够作为膳食补充剂,用于改善血液胆固醇和研究痤疮。 |