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Cat. No.	Product Name	Target	Signaling Pathways
T72771	p53 Activator 7	Apoptosis	Apoptosis
	p53 Activator 7 是一种高效性和细胞渗透性的 p53 突变 Y220C (MDM-2/p53) 激活剂，可诱导细胞凋亡。
T26840	BMH-7 BMH7
	BMH-7 is a p53 activator with potent antitumor activity.
T36464	Caylin-1
	Nutlin-3 is an activator of p53 that functions by inhibiting the interaction of p53 with MDM2, a negative regulator of p53 activity. Caylin-1 is a nutlin-3 analog which contains chlorine substituents at the 3 and 4 positions on two of the phenyl rings rather than a single 4-chloro as seen in nutlin-3. At high concentrations, caylin-1 inhibits the growth of HCT116 cells with an IC50 value of approximately 7 μM, making it about 7-fold less potent than nutlin-3 in the same assay. Interestingly, at ...