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Cat. No. Product Name Target Signaling Pathways
T35648 4-Thiouridine

Others Others
4-Thiouridine (4-TU) 是一种光活化核糖核苷类似物,广泛用于RNA 分析。
T12006 Metarrestin

ML246

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Metarrestin (ML246) 是一种口服有效的选择性核仁周区室 (PNC) 抑制剂,可有效抑制转移。Metarrestin 破坏核仁结构并抑制 RNA 聚合酶 (Pol) I 转录,部分是通过与翻译延伸因子 eEF1A2 的相互作用。
T23802 BMH-22

BMH22

BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.
T23804 BMH-9

BMH 9

BMH-9 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.
T23803 BMH-23

BMH23,BMH 23

BMH-23 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.
T68859 Rudolfomycin

Rudolfomycin is a class II anthracycline antitumor antibiotic that inhibit the synthesis of nucleolar RNA in intact tumor cells.
T73724 WDR5-IN-4 TFA

WDR5-IN-4 TFA 是一种染色质相关 WD 重复结构域 5 蛋白 (WDR5) 的 WIN 位点抑制剂,Kd 值为 0.1 nM。WDR5-IN-4 TFA 能够从染色质中取代 WDR5,并降低相关基因的表达,引起翻译抑制和核仁应激。具有抗癌作用。
T69908 Pidnarulex HCl

Pidnarulex HCl is the salt form of CX-5461, a first-in-class non-genotoxic small molecule targeted inhibitor of RNA polymerase I (Pol I) that activates the p53 pathway without causing DNA damage. CX-5461 selectively inhibits rRNA synthesis by Pol I in the nucleolus, but does not inhibit mRNA synthesis by RNA Polymerase II (Pol II) and does not inhibit DNA replication or protein synthesis. Inhibition of Pol I results in nucleolar stress and release of ribosomal proteins (RP) from the nucleolus. T...

化合物

4-Thiouridine
Cat.No: T35648
Synonym:
Target: Others
Metarrestin
Cat.No: T12006
Synonym: ML246
Target: DNA/RNA Synthesis
BMH-22
Cat.No: T23802
Synonym: BMH22
Target:
BMH-9
Cat.No: T23804
Synonym: BMH 9
Target:
BMH-23
Cat.No: T23803
Synonym: BMH23,BMH 23
Target:
Rudolfomycin
Cat.No: T68859
Synonym:
Target:
WDR5-IN-4 TFA
Cat.No: T73724
Synonym:
Target:
Pidnarulex HCl
Cat.No: T69908
Synonym:
Target:
TargetMol Loading
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