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Cat. No. | Product Name | Target | Signaling Pathways |
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T22517 |
5,7-Dichlorokynurenic acid
5,7-二氯犬尿喹啉酸,5,7-dichlorokynurenic acid sodium,5,7-DCKA |
NMDAR | Neuroscience |
5,7-Dichlorokynurenic acid (5,7-dichlorokynurenic acid sodium) 是一种专门针对于NMDA 受体甘氨酸位点的竞争性拮抗剂(KB:65 nM)。它是犬尿酸的衍生物,可降低大鼠皮质细胞培养物中 NMDA 诱导的神经元损伤程度。 | |||
T36903 |
Rasagiline-13C3 (mesylate)
Rasagiline-13C3 (mesylate) |
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Rasagiline-13C3is intended for use as an internal standard for the quantification of rasagiline by GC- or LC-MS. Rasagiline is an inhibitor of monoamine oxidase B (MAO-B; IC50= 4.43 nM for the rat brain enzyme).1It is selective for MAO-B over MAO-A (IC50= 412 nM for the rat brain enzyme). It inhibits serum and NGF withdrawal-induced apoptosis of PC12 cells when used at concentrations ranging from 0.01 to 100 μM.2Rasagiline inhibits rat brain MAO-Bin vivo(ED50= 0.1 mg/kg).1It reduces cerebral ede... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T4S2084 |
3'-Methoxypuerarin
3'-甲氧基葛根素,3’- Methoxy Puerarin |
Antioxidant | oxidation-reduction |
3'-Methoxypuerarin 是一种提取自葛根中的异黄酮,具有神经元保护作用。 |