Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5194 |
SPHINX31
|
Serine/threonin kinase | Cell Cycle/Checkpoint; Metabolism |
SPHINX31 是丝氨酸/富含精氨酸的蛋白激酶1的选择性抑制剂,其IC50值为 5.9 nM。它有效抑制丝氨酸/丰富精氨酸的剪接因子1 磷酸化,有用于局部新生血管性眼病的研究潜力。 | |||
T69452 |
AG-13958 monohydrochloride
|
||
AG-13958 monohydrochloride is the HCl salt of AG-13958 --- a VEGFA inhibitor potentially for the treatment of age-related macular degeneration. Neovascular AMD, a subtype characterized by the growth of new, pathologic blood vessels, results in most of the cases of severe and rapid vision loss associated with AMD. A critical activator of angiogenesis in neovascular AMD is VEGF. | |||
T39706 | Pegaptanib sodium | ||
Pegaptanib sodium, an RNA aptamer specifically targeting vascular endothelial growth factor (VEGF)-165, holds great promise for investigating neovascular age-related macular degeneration (AMD). | |||
T36620 |
ALK4290
ALK4290 |
||
ALK4290 (AKST4290) is a potent and orally actively CCR3 inhibitor, compound Example 2, with a Ki of 3.2 nM for hCCR3[1]. ALK4290 can be used for the research of neovascular age-related macular degeneration and Parkinsonism[2][3]. | |||
T76887 | Rinucumab | ||
Rinucumab (REGN 2176) 是一种单克隆抗体,是PDGF 的抑制剂。Rinucumab (REGN 2176) 可用于新生血管性年龄相关性黄斑变性的研究。 | |||
T82641 |
Cyclo(RGDyC)
|
||
Cyclo(RGDyC) 是环状五肽,有抗血管生成作用。可结合脂质体递送系统,用于研究眼部新生血管疾病及癌症。 |