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Cat. No. Product Name Target Signaling Pathways
T5194 SPHINX31

Serine/threonin kinase Cell Cycle/Checkpoint; Metabolism
SPHINX31 是丝氨酸/富含精氨酸的蛋白激酶1的选择性抑制剂,其IC50值为 5.9 nM。它有效抑制丝氨酸/丰富精氨酸的剪接因子1 磷酸化,有用于局部新生血管性眼病的研究潜力。
T69452 AG-13958 monohydrochloride

AG-13958 monohydrochloride is the HCl salt of AG-13958 --- a VEGFA inhibitor potentially for the treatment of age-related macular degeneration. Neovascular AMD, a subtype characterized by the growth of new, pathologic blood vessels, results in most of the cases of severe and rapid vision loss associated with AMD. A critical activator of angiogenesis in neovascular AMD is VEGF.
T39706 Pegaptanib sodium

Pegaptanib sodium, an RNA aptamer specifically targeting vascular endothelial growth factor (VEGF)-165, holds great promise for investigating neovascular age-related macular degeneration (AMD).
T36620 ALK4290

ALK4290

ALK4290 (AKST4290) is a potent and orally actively CCR3 inhibitor, compound Example 2, with a Ki of 3.2 nM for hCCR3[1]. ALK4290 can be used for the research of neovascular age-related macular degeneration and Parkinsonism[2][3].
T76887 Rinucumab

Rinucumab (REGN 2176) 是一种单克隆抗体,是PDGF 的抑制剂。Rinucumab (REGN 2176) 可用于新生血管性年龄相关性黄斑变性的研究。
T82641 Cyclo(RGDyC)

Cyclo(RGDyC) 是环状五肽,有抗血管生成作用。可结合脂质体递送系统,用于研究眼部新生血管疾病及癌症。

化合物

SPHINX31
Cat.No: T5194
Synonym:
Target: Serine/threonin kinase
AG-13958 monohydrochloride
Cat.No: T69452
Synonym:
Target:
Pegaptanib sodium
Cat.No: T39706
Synonym:
Target:
ALK4290
Cat.No: T36620
Synonym: ALK4290
Target:
Rinucumab
Cat.No: T76887
Synonym:
Target:
Cyclo(RGDyC)
Cat.No: T82641
Synonym:
Target:
TargetMol Loading
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