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22

抑制剂 & 化合物

14

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T35734	Doramectin monosaccharide
	Doramectin monosaccharide is an acid degradation product of doramectin , a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. Doramectin undergoes acid-catalyzed hydrolysis to form doramectin monosaccharide.
T35744	Ivermectin B1a monosaccharide
	Ivermectin B1a monosaccharide is produced by selective hydrolysis of the terminal saccharide unit of ivermectin. It can inhibit nematode larval development, but does not cause paralytic activity. This compound has been used as a probe to detect some types of ivermectin resistance.
T35756	Avermectin B1a monosaccharide
	Avermectin B1a monosaccharide is a macrolide anthelmintic and monosaccharide form of avermectin B1a . It is lethal to C. elegans with a minimum active concentration (MAC) value of 0.1 μM. Avermectin B1a monosaccharide also stimulates conductance in isolated shore crab muscle.
T0582	Fructooligosaccharides	Others	Others
	Fructooligosaccharides 是一种左旋单糖，是葡萄糖的异构体。
T37986	D-Mannose-6-Phosphate sodium salt hydrate	Others	Others
	D-Mannose-6-Phosphate sodium salt hydrate 是一种多功能单糖，可用于研究代谢、溶酶体传递和癌症。
T77348	Butylboronicacid	Others	Others
	Butylboronicacid 是脲酶竞争性抑制剂，可作为单糖络合试剂。
T67690	pNPG-1 4-Nitrophenyl β-D-glucuronide	Others	Others
	pNPG-1(4-Nitrophenyl β-D-glucuronide) 是一种葡萄糖醛酸单糖衍生物，是β-葡糖苷酶的显色底物。
T22352	L-Gulose	Others; Endogenous Metabolite	Metabolism; Others
	L-Gulose 是一种合成维生素 C 的生物中间体，是一种 L-sorbosone 的呋喃糖形式，是L 己糖。
T32778	Lipid X
	Lipid X is a monosaccharide precursor of E coli lipid A.
T35733	Doramectin aglycone
	Doramectin aglycone is an acid degradation product of doramectin , a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes, and its acid-catalyzed hydrolysis product doramectin monosaccharide . Doramectin undergoes one round of acid-catalyzed hydrolysis to form doramectin monosaccharide which is then hydrolyzed again to remove the remaining saccharide unit and form doramectin aglycone.
T34770	Tagatose
	Tagatose is a sweetener based on its properties as a monosaccharide, specifically a hexose.
T32779	Lipid Y
	Lipid Y is a monosaccharide precursor of E coli lipid A.
T68903	Pyrromycin
	Pyrromycin is a monosaccharide anthracycline which can be used to inhibit cellular RNA synthesis.
T63779	RmlA-IN-2
	RmlA-IN-2 是 1-磷酸葡萄糖胸苷转移酶 (RmlA) 的有效抑制剂 (IC50: 0.303 μM)。RmlA-IN-2 能够影响单糖 l-鼠李糖生物合成途径，并影响细菌细胞壁通透性。
T19299	DTE Cleland’s reagent,Dithioerythritol	Others	Others
	Dithioerythritol (DTE), a sulfur-containing sugar derivative of the 4-carbon monosaccharide erythrose, is an epimer of dithiothreitol (DTT).
T19260	D-Erythrose 4-phosphate sodium	Others	Others
	D-erythrose 4-sodium phosphate is the sodium phosphate of the monosaccharide erythrose. Erythritol is actually converted to D-erythrose 4-phosphate involving three isomerases.
T61715	RmlA-IN-1
	RmlA-IN-1 (Compound 8a) is a highly potent inhibitor of glucose-1-phosphate thymidylyltransferase (RmlA), with an IC50 value of 0.073 μM. It significantly modulates the biosynthesis of monosaccharide l-Rhamnose and impacts the permeability of the bacterial cell wall [1].
T35442	1-Amino-1-deoxy-D-fructose (hydrochloride)
	1-Amino-1-deoxy-D-fructose is an amino monosaccharide.1It induces site-specific DNA damage at pyrimidine residues in cell-free assays. 1-Amino-1-deoxy-D-fructose moieties have been found as a component of fructosamines, glycated serum proteins that are elevated in patients with conditions such as diabetes.2,3
T36111	L-Iduronic acid sodium salt
	L-Iduronic acid sodium salt 是一种单糖，是肝素、硫酸乙酰肝素和硫酸皮肤素等糖胺聚糖 (GAG) 的重要成分。
T37987	D-Ribulose
	Ribulose is a ketopentose, a monosaccharide containing five carbon atoms and a ketone functional group. It is synthesized in the pentose phosphate pathway and plays a role in the formation of various bioactive compounds. It is a structural isomer of ribose and exists as two enantiomers, D-ribulose and L-ribulose. A double phosphate ester of D-ribulose, ribulose-1,5-bisphosphate combines with carbon dioxide at the beginning of photosynthesis.
T38027	Ganglioside GM2 Asialo Mixture Ganglioside GM2 Asialo Mixture
	Ganglioside GM2 asialo (asialo- GM2) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2. Asialo-GM2 levels are low-to-undetectable in normal human brain, but it accumulates in the brain of patients with Tay-Sachs and Sandhoff disease, which are neurodegenerative disorders characterized by deficiency of lysosomal β-hexosaminidase A and B, respectively. It also binds to various bact...
T37347	6'-Sialyllactose Sodium Salt 6'-Sialyllactose Sodium Salt,6'-N-Acetylneuraminyl-D-lactose
	6'-Sialyllactose consists of the monosaccharide N-acetylneuraminic acid linked to the galactosyl subunit of lactose at the 6 position. This connection is at the 3 position in the related compound, 3’-sialyllactose. Both are major milk oligosaccharides that avidly bind several viral strains, including strains of influenza, HIV-1, reovirus, and polyomavirus.[1],[2],[3],[4],[5],[6] These compounds can be used to differentiate and characterize the binding domains of viruses that recognize N-acetylne...

化合物

Doramectin monosaccharide

Cat.No: T35734

Ivermectin B1a monosaccharide

Cat.No: T35744

Avermectin B1a monosaccharide

Cat.No: T35756

Fructooligosaccharides

Cat.No: T0582

Target: Others

D-Mannose-6-Phosphate sodium salt hydrate

Cat.No: T37986

Target: Others

Butylboronicacid

Cat.No: T77348

Target: Others

Cat.No: T67690

Synonym: 4-Nitrophenyl β-D-glucuronide

Target: Others

Cat.No: T22352

Target: Others, Endogenous Metabolite

Cat.No: T32778

Doramectin aglycone

Cat.No: T35733

Cat.No: T34770

Cat.No: T32779

Cat.No: T68903

Cat.No: T63779

Cat.No: T19299

Synonym: Cleland’s reagent,Dithioerythritol

Target: Others

D-Erythrose 4-phosphate sodium

Cat.No: T19260

Target: Others

Cat.No: T61715

1-Amino-1-deoxy-D-fructose (hydrochloride)

Cat.No: T35442

L-Iduronic acid sodium salt

Cat.No: T36111

Cat.No: T37987

Ganglioside GM2 Asialo Mixture

Cat.No: T38027

Synonym: Ganglioside GM2 Asialo Mixture

6'-Sialyllactose Sodium Salt

Cat.No: T37347

Synonym: 6'-Sialyllactose Sodium Salt,6'-N-Acetylneuraminyl-D-lactose

Cat. No.	Product Name	Target	Signaling Pathways
T4733	Sucrose D(+)-Sucrose,D-(+)-Saccharose,蔗糖	Others; Endogenous Metabolite	Metabolism; Others
	Sucrose (D-(+)-Saccharose) 是一种二糖，由果糖和葡萄糖组成。Sucrose 能够应用于一些动物模型，包括代谢性疾病、偏食、肥胖、糖尿病等。
T6559	Rhamnose monohydrate L-鼠李糖,L-(+)-Rhamnose Monohydrate	Others	Others
	Rhamnose monohydrate (L-(+)-Rhamnose Monohydrate) 是一种存在植物和细菌中的单糖。它能通过胞外途径穿过上皮细胞，可以作为肠吸收的标志。Rhamnose monohydrate 免疫原连接物能被用于免疫疗法。
T5120	Rhamnose 6-Deoxyhexopyranose,L-鼠李糖,6-Deoxy-L-mannose,alpha-L-Rhamnose	Calcium Channel; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism
	alpha-L-Rhamnose (6-Deoxy-L-mannose) 是存在植物和细菌中的一种单糖。Rhamnose- 免疫原连接物能被用于免疫疗法。Rhamnose 能通过胞外途径穿过上皮细胞，能够作为肠吸收的标志。
T0032	DL-Xylose Hexadecylphosphocholine,Xylose,(±)-Xylose,(±)-Xylos,木糖	Others	Others
	DL-Xylose ((±)-Xylos) 是有机合成过程的一种中间体。
T2954	Fructose Fructopyranose,果糖	Others	Others
	Fructose (Fructopyranose) 是一种酮类单糖，在许多植物中发现。它通常与葡萄糖结合形成二糖蔗糖。
T15700	L-Xylose L-(-)-Xylose,L-(-)木糖	Others	Others
	L-Xylose (L-(-)-Xylose) 是一种木糖的左旋结构。其中木糖是醛戊糖类型的单糖。
T4514	N-Acetyl-D-Glucosamine N-乙酰-D-氨基葡萄糖,NAG,N-Acetyl-2-amino-2-deoxyglucose,Marine Sweet,N-Acetyl-2-amino-2-deoxy-D-glucose,N-乙酰氨基葡萄糖,GlcNAc	Endogenous Metabolite	Metabolism
	N-Acetyl-D-Glucosamine (NAG) 是葡萄糖的单糖衍生物。
T0592	D-Mannopyranose Mannose,D-甘露糖	Others	Others
	D-Mannopyranose (Mannose) 是一种己糖或可发酵单糖，是甘露糖、水曲柳和相关植物的葡萄糖异构体。
TN6826	D-Xylose (2S,3R,4S,5R)-oxane-2,3,4,5-tetrol
	D-Xylose ((2S,3R,4S,5R)-oxane-2,3,4,5-tetrol)是一种广泛存在于酵母菌中的单糖，参与生物体的代谢。
T5546	Helicin 绣线菊苷,Helecin	Others	Others
	Helicin (Helecin) 是一种发现于在蔷薇科中的syrB 诱导剂。其中BglY 酶可水解 Helicin。
T4869	D-Allose 阿洛糖,β-D-Allopyranose,D-(+)-ALLOSE	Others; Endogenous Metabolite	Metabolism; Others
	D-Allose (β-D-Allopyranose) 是内源性代谢产物的一种。
T1638	N-Acetylneuraminic acid 唾液酸,Acide aceneuramique,N-乙酰神经氨酸,NeuAc,Lactaminic acid	Others; Influenza Virus; Endogenous Metabolite	Metabolism; Microbiology/Virology; Others
	N-Acetylneuraminic acid (Acide aceneuramique) 是一种九碳唾液酸单糖，通常存在于细胞膜上的糖蛋白和哺乳动物细胞中的神经节苷脂等糖脂中。它可用于神经传递、白细胞外渗、病毒或细菌感染以及碳水化合物-蛋白质识别。
T4725	N-Acetyl-D-mannosamine N-乙酰-D-甘露糖胺,2-ACETAMIDO-2-DEOXY-D-MANNOPYRANOSE HYDRATE	Others; Endogenous Metabolite	Metabolism; Others
	N-Acetyl-D-mannosamine (2-ACETAMIDO-2-DEOXY-D-MANNOPYRANOSE HYDRATE) 是一种单糖，在糖脂和糖蛋白中发现的神经氨酸的化学或酶合成中用作前体。N-Acetyl-D-mannosamine 是合成细菌荚膜聚唾液酸(PA)必需前体n -乙酰神经氨酸的特异性底物。N-Acetyl-D-mannosamine 用于合成唾液酸。它也是许多碳水化合物衍生的生物活性化合物家族和候选药物的合成中间体。
T4825	D-(+)-Xylose D(+)-Xylose,木糖,(+)-Xylose,Wood sugar	Endogenous Metabolite	Metabolism
	D-(+)-Xylose (Wood sugar) 是一种是一种戊醛糖，其化学式为C5H10O5，甜度为蔗糖的40%。木糖也存在于结缔组织的粘多糖中，有时也存在于尿液中。

天然产物

Cat.No: T4733

Synonym: D(+)-Sucrose,D-(+)-Saccharose,蔗糖

Target: Others, Endogenous Metabolite

Rhamnose monohydrate

Cat.No: T6559

Synonym: L-鼠李糖,L-(+)-Rhamnose Monohydrate

Target: Others

Cat.No: T5120

Synonym: 6-Deoxyhexopyranose,L-鼠李糖,6-Deoxy-L-mannose,alpha-L-Rhamnose

Target: Calcium Channel, Endogenous Metabolite

Cat.No: T0032

Synonym: Hexadecylphosphocholine,Xylose,(±)-Xylose,(±)-Xylos,木糖

Target: Others

Cat.No: T2954

Synonym: Fructopyranose,果糖

Target: Others

Cat.No: T15700

Synonym: L-(-)-Xylose,L-(-)木糖

Target: Others

N-Acetyl-D-Glucosamine

Cat.No: T4514

Synonym: N-乙酰-D-氨基葡萄糖,NAG,N-Acetyl-2-amino-2-deoxyglucose,Marine Sweet,N-Acetyl-2-amino-2-deoxy-D-glucose,N-乙酰氨基葡萄糖,GlcNAc

Target: Endogenous Metabolite

D-Mannopyranose

Cat.No: T0592

Synonym: Mannose,D-甘露糖

Target: Others

Cat.No: TN6826

Synonym: (2S,3R,4S,5R)-oxane-2,3,4,5-tetrol

Cat.No: T5546

Synonym: 绣线菊苷,Helecin

Target: Others

Cat.No: T4869

Synonym: 阿洛糖,β-D-Allopyranose,D-(+)-ALLOSE

Target: Others, Endogenous Metabolite

N-Acetylneuraminic acid

Cat.No: T1638

Synonym: 唾液酸,Acide aceneuramique,N-乙酰神经氨酸,NeuAc,Lactaminic acid

Target: Others, Influenza Virus, Endogenous Metabolite

N-Acetyl-D-mannosamine

Cat.No: T4725

Synonym: N-乙酰-D-甘露糖胺,2-ACETAMIDO-2-DEOXY-D-MANNOPYRANOSE HYDRATE

Target: Others, Endogenous Metabolite

Cat.No: T4825

Synonym: D(+)-Xylose,木糖,(+)-Xylose,Wood sugar

Target: Endogenous Metabolite

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