Cat. No. | Product Name | Target | Signaling Pathways |
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T0203 |
Sumatriptan succinate
舒马普坦琥珀酸盐,GR 43175,琥珀酸舒马曲坦 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Sumatriptan succinate (GR 43175) 是一种5-HT1受体激动剂,可作用于偏头疼的急性治疗。 | |||
T26079 |
RI 61
RI-61,Pro-his-pro-phe-his-leu-phe-val-phe,RI61 |
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RI 61 (sumatriptan succinate) is utilized in the therapy of migraine, cluster headaches, new daily persistent headache, and cyclic vomiting syndrome. | |||
T60345 |
Frovatriptan
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Frovatriptan is a highly potent agonist of the 5-HT 1B//D receptors, exhibiting the highest potency among triptan compounds. It possesses prominent cerebroselectivity. Frovatriptan demonstrates efficacy and even superiority in certain endpoints, including when administered during the headache phase of migraine attacks accompanied by aura [1]. | |||
T60989 |
Sumatriptan hydrochloride
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Sumatriptan (GR 43175) hydrochloride 可用于研究偏头痛,它是一种口服有效的5-HT1受体激动剂。Sumatriptan hydrochloride 对5-HT1D、5-HT1B 和5-HT1A 受体的 Ki 值分别为 17 nM、27 nM 和 100 nM。 |