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14

抑制剂 & 化合物

4

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T8788	Naptalam	Others	Others
	Naptalam 是一种极性生长素转运抑制剂。它能够对玉米叶片起始、KNOX 蛋白调节和叶缘形成造成破坏。
T8377	Mesotrione 甲基磺草酮,硝磺草酮	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Mesotrione 是一种苯甲酰环己二酮类除草剂，是一种竞争性羟基苯基丙酮酸双加氧酶酶抑制剂。它对玉米作物具有选择性，它在易感作物中代谢速度快，耐受性较高。
T2023	MC1568	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	MC1568是一种针对玉米 HD1-A 的特异性 HDAC 抑制剂，在无细胞试验中的IC50为100 nM，可用于癌症研究。
T20103	Isoxadifen-ethyl Isoxadifen-ethyl	Others	Others
	Isoxadifen-ethyl 是除草剂安全剂和农用化学品。 Isoxadifen-ethyl 可有效减轻烟嘧磺隆对玉米的损伤。
T9897	7-Methoxy-1-naphthaleneacetic acid	Others	Others
	7-Methoxy-1-naphthaleneacetic acid 是植物生长素作用的抑制剂。 7-Methoxy-1-naphthaleneacetic acid 抑制与拟南芥和玉米中生长素不对称分布相关的极性生长素转运和热带反应。 7-Methoxy-1-naphthaleneacetic acid 抑制由酵母中表达的 AUX1、PIN 和 ABCB 蛋白介导的生长素转运。
T69237	Phosphoenol-3-bromopyruvate
	Phosphoenol-3-bromopyruvate is a mechanism-based inhibitor of phosphoenolpyruvate carboxylase from maize
T39157	Bromoxynil octanoate
	Bromoxynil octanoate, a widely used herbicide in maize cultivation, possesses potential toxicity towards both animals and humans.
T30618	Butachlor 丁草胺,NSC 221683,CP 53619,SHA 112301,BRN 2873811
	Butachlor is a chloroacetanalide herbicide. Butachlor is commonly used for weed control in rice as well as cotton, maize, wheat and other crops.
T74157	Transketolase-IN-1
	Transketolase-IN-1是一种很有希望的除草剂，可用于小麦和玉米田的杂草防治，其作用靶点为 Transketolase。
T38615	Rimsulfuron DPX-E9636,Rimsulfuron
	Rimsulfuron (DPX-E9636) is a sulfonylurea herbicide specifically designed for postemergence application in maize crops. This compound effectively targets and manages grasses as well as certain types of broadleaf weeds.
T35774	HC Toxin
	HC Toxin is a cell-permeable, reversible inhibitor of histone deacetylases (HDACs) (IC50 = 30 nM). Through its effects on HDACs, HC toxin has been shown to up-regulate the expression of 15-lipoxygenase-1 in colorectal cancer cells and induce fetal hemoglobin in human primary erythroid cells. HC Toxin is a cyclic tetrapeptide first isolated from H. carbonum (now C. carbonum), a pathogen of maize.
T80642	Foramsulfuron
	Foramsulfuron作为磺酰脲类除草剂，专用于玉米(Zea mays L.)中选择性地防控禾本科以及部分阔叶杂草。该化合物通过抑制关键酶乙酰乳酸合酶(acetolactate synthase, ALS)的活性，从而表现出对杂草的抑制功能，ALS主导支链氨基酸的生物合成途径。
T35783	Zearalenone-13C18 Zearalenone-13C18
	Zearalenone-13C18is intended for use as an internal standard for the quantification of zearalenone by GC- or LC-MS. Zearalenone is a mycotoxin that has been found inFusariumand has estrogenic activities.1It binds to human estrogen receptor α (ERα) and ERβ (IC50s = 9 and 5.8 nM, respectively).2Zearalenone induces precocious development of mammary tissues in young female pigs and prepucial enlargement in young male pigs.3Zearalenone (1.5-5 mg/kg of diet) induces hyperestrogenism in pigs. It also i...
T37971	12-oxo-13-HOME
	12-oxo-13-HOME is an oxylipin derived from linoleic acid .1It is formedviaa 13-HpODE intermediate that is produced by lipoxygenase-mediated metabolism of linoleic acid.2,3,112-oxo-13-HOME has been found in corn and sunflower seedlings.4 1.Ogorodnikova, A.V., Gorina, S.S., Mukhtarova, L.S., et al.Stereospecific biosynthesis of (9S,13S)-10-oxo-phytoenoic acid in young maize rootsBiochim. Biophys. Acta1851(9)1262-1270(2015) 2.Veldink, G.A., and Vliegenthart, J.F.G.The enzymic conversions of 13-hydr...

化合物

Cat.No: T8788

Target: Others

Cat.No: T8377

Synonym: 甲基磺草酮,硝磺草酮

Target: Reactive Oxygen Species

Cat.No: T2023

Target: HDAC

Isoxadifen-ethyl

Cat.No: T20103

Synonym: Isoxadifen-ethyl

Target: Others

7-Methoxy-1-naphthaleneacetic acid

Cat.No: T9897

Target: Others

Phosphoenol-3-bromopyruvate

Cat.No: T69237

Bromoxynil octanoate

Cat.No: T39157

Cat.No: T30618

Synonym: 丁草胺,NSC 221683,CP 53619,SHA 112301,BRN 2873811

Transketolase-IN-1

Cat.No: T74157

Cat.No: T38615

Synonym: DPX-E9636,Rimsulfuron

Cat.No: T35774

Cat.No: T80642

Zearalenone-13C18

Cat.No: T35783

Synonym: Zearalenone-13C18

Cat.No: T37971

Cat. No.	Product Name	Target	Signaling Pathways
T6S0920	2"-O-Galloylhyperin 2”-O-没食子酰基金丝桃苷,2''-O-Galloylhyperin,Q-100605,FT-0689359	Others	Others
	2"-O-Galloylhyperin (FT-0689359) 是一种分离自Pyrola incarnateFisch. 中的活性化合物，具有抗氧化和抗炎作用，对氧化应激诱导的肝损伤具有肝保护作用。
T3897	Isoschaftoside	Anti-infection; Antifungal	Microbiology/Virology
	Isoschaftosid 是从 Desmodium uncinatum 根部分泌物中提取的 c- 糖基黄酮类天然产物，有抗肿瘤、抗氧化和抗菌活性，它还对 M. incognita 具有很强的杀线虫活性。
T12313	Ophiobolin B	Others	Others
	Ophiobolin B is a sesterterpene Helminthosporium oryzae metabolite, inhibits proton extrusion from maize coleoptiles.
T36749	Herboxidiene
	Herboxidiene is a polyketide originally isolated from S. chromofuscus that has diverse biological activities.[1],[2,][3],[4],[5] It inhibits growth of HeLa S3, SK-MEL-2, PC3, A549, and EBC-1 cells with GI50 values ranging from 7.4 to 62 nM.3 Herboxidiene is cytostatic against human umbilical vein endothelial cells (HUVECs; (IC50 = 26 nM)) and inhibits VEGF-induced invasion and tube formation of serum-starved HUVECs in a concentration-dependent manner, indicating antiangiogenic activity.[4] Herbo...

天然产物

2"-O-Galloylhyperin

Cat.No: T6S0920

Synonym: 2”-O-没食子酰基金丝桃苷,2''-O-Galloylhyperin,Q-100605,FT-0689359

Target: Others

Cat.No: T3897

Target: Anti-infection, Antifungal

Cat.No: T12313

Target: Others

Cat.No: T36749

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