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Cat. No. | Product Name | Target | Signaling Pathways |
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T82483 |
Elastase LasB-IN-1
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ElastaseLasB-IN-1 (Compound 4b) 是一种选择性弹性蛋白酶LasB抑制剂,展现出抗菌活性,其IC50值为76 nM。 |
Cat. No. | Product Name | Target | Signaling Pathways |
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T38373 |
2-heptyl-3-hydroxy-4(1H)-Quinolone
2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal |
Others | Others |
2-heptyl-3-hydroxy-4(1H)-Quinolone (Pseudomonas Quinolone Signal) 是一种铜绿假单胞菌为应对细胞密度增加而产生的一种法定人数感应信号分子。 它增加了铜绿假单胞菌中lasB 基因的表达,增加代谢物焦蓝蛋白和凝集素PA-IL 的分泌,以及增加铜绿假单胞菌种群的生物膜生产。当使用浓度为40 μM 时,它还会降低铜绿假单胞菌生长介质中的铁含量,并在硫酸铁溶液中充当一种铁螯合剂。 |
Cat. No. | Product Name | Species | Expression System |
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TMPH-03166 |
Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)
PAE,lasB,Pseudolysin,Neutral metalloproteinase,Elas... |
Pseudomonas aeruginosa | E. coli |
Cleaves host elastin, collagen, IgG, and several complement components as well as endogenous pro-aminopeptidase. Autocatalyses processing of its pro-peptide. Processes the pro-peptide of pro-chitin-binding protein (cbpD). Involved in the pathogenesis of P.aeruginosa infections. Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.1 kDa and the accession number is P14756. | |||
TMPH-03177 |
RhlR Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO)
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Pseudomonas aeruginosa | E. coli |
Necessary for transcriptional activation of the rhlAB genes encoding the rhamnosyltransferase. It also functions as a transcriptional activator of elastase structural gene (lasB). Binds to autoinducer molecules BHL (N-butanoyl-L-homoserine lactone), and HHL (N-hexanoyl-L-homoserine lactone). RhlR Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 47.6 kDa and the accession n... |