11
2
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T19332 |
Gadopentetic acid
gadolinium complex,钆喷酸,Gd-DTPA |
Others | Others |
Gadopentetic acid (gadolinium complex) 是一种顺磁性造影剂,通常通过静脉内注射 (i.v.) 的方式用于 DCE-MRI 研究。 | |||
T28466 |
PSMA-11
HBED-CC-PSMA,Psma-hbed-CC,PSMA11 |
||
PSMA-11 (HBED-CC-PSMA)通过与前列腺特异性膜抗原(PSMA)的细胞外结构域结合来检测前列腺癌的复发和转移。PSMA-11常被用作正电子发射断层扫描(PET)中用作表达PSMA 的肿瘤的示踪剂,通过静脉注射镓Ga 68标记的PSMA-11,Glu-urea-Lys(Ahx)分子靶向并结合表达PSMA 的肿瘤细胞。内化后,PSMA 表达的肿瘤细胞可在PET 成像中被检测到。 | |||
T26230 |
Stilbamidine dihydrochloride
NSC 35605,NCI 174 |
||
Stilbamidine dihydrochloride is a blocker of neuromuscular transmission and axonal conduction used to study the distribution of the drug in the organs and tissues of rats following intravenous injection. | |||
T37027 |
MHAPC-Chol
|
||
MHAPC-Chol is a cationic cholesterol. MHAPC-Chol, as part of a lipoplex with DOPE , has been used for siRNA delivery and gene silencing in MCF-7 cells in a luciferase assay without affecting cell viability. It has also been used to deliver siRNA into mice via intravenous injection, resulting in MHAPC-chol accumulation in the liver. | |||
T37017 |
OH-C-Chol
|
||
OH-C-Chol is a cationic cholesterol derivative. OH-C-Chol, as a component of lipoplexes with DOPE , has been used for siRNA delivery and gene silencing in MCF-7 cells as well as in mice via intravenous injection, resulting in lipoplex accumulation in the liver. | |||
T37035 |
HAPC-Chol
|
||
HAPC-Chol is a cationic cholesterol. HAPC-Chol, as part of a lipoplex with DOPE , has been used for siRNA delivery and gene silencing in MCF-7 cells in a luciferase assay without affecting cell viability. It has also been used to deliver siRNA into mice via intravenous injection, resulting in HAPC-chol accumulation in the lungs. | |||
T37018 |
OH-Chol
|
||
OH-Chol is a cationic cholesterol derivative.1 OH-Chol, as a component of lipoplexes with DOPE , has been used for siRNA delivery and gene silencing in MCF-7 cells, as well as in mice via intravenous injection, resulting in lipoplex accumulation in the liver. It has also been used in cationic nanoparticles in combination with Tween 80 to transfect pDNA and siRNA into PC3 mouse xenografts via intratumoral injection and with Tween 80 and folate-PEG2000-DSPE in a KB mouse xenograft model for intrat... | |||
T33785 |
o-Iodohippurate sodium
Hippodin,NSC-63351,Sodium iodohippurate NSC 63351,NSC63351 |
||
o-Iodohippurate sodium is an analogue of p-aminohippuric acid used to determine effective renal plasma flow. Labelled OIH has a higher clearance than other radiopharmaceutical yet developed and is extremely suitable for renography. It is eliminated mainly | |||
T38319 |
93-O17O
93-O17O |
||
93-O17O is a chalcogen-containing cationic lipidoid.1,2It has been used in the generation of lipid nanoparticles (LPNs). LPNs containing 93-O17O localize to the spleen after intravenous injection into mice.1LPNs containing 93-O17O have been used for the delivery of Cre recombinase and ribonucleoproteins for genome editing in mice and for the intratumoral delivery of cGAMP to enhance cross-presentation of tumor antigens.3,2 1.Zhao, X., Chen, J., Qiu, M., et al.Imidazole-based synthetic lipidoids ... | |||
T71251 |
DS-1558
|
||
DS-1558 is a potent and orally available GPR40 agonist.DS-1558 was found to have potent glucose lowering effects during an oral glucose tolerance test in ZDF rats. DS-1558 significantly and dose-dependently improved hyperglycemia and increased insulin secretion during the oral glucose tolerance test in Zucker fatty rats, the model of insulin resistance and glucose intolerance. DS-1558 not only increased the glucose-stimulated insulin secretion by GLP-1 but also potentiated the maximum insulinog... | |||
T35527 |
PI3Kα-IN-4
PI3Kα-IN-4 |
||
PI3Kα-IN-4 is a potent, selective and orally active inhibitor of PI3Kα, with an IC50 of 1.8 nM. PI3Kα-IN-4 has antitumor activity[1]. PI3Kα-IN-4 (compound 10) inhibits PI3Kα, β, δ, and γ, with IC50s of 1.8, 271.0, 13.9, and 13.8 nM, respectively in kinase assays[1].PI3Kα-IN-4 inhibits PI3Kα, β, δ, and γ, with IC50s of 12.1,1393, 183, and >10000 nM, respectively in cell based assays[1]. PI3Kα-IN-4 (compound 10) (30 mg/kg; p.o. once daily for 21 d) achieves the best efficacy, which could inhibit t... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TCS1704 |
Artemitin
艾黄素,Artemetin,Artemisetin,Erianthin |
Antioxidant | oxidation-reduction |
Artemitin (Erianthin) 是一种存在于翼齿六棱菊中的天然黄酮,具有抗氧化、抗炎、抗病毒活性。 | |||
TL0018 |
Lobelin
|
AChR; Antifection | Microbiology/Virology; Neuroscience |
Inhalation challenge with capsaicin and rapid intravenous injection of Lobelin and alinamin indicated that peripheral c-fiber receptors were involved in the induction of coughing. |