首页工具

登录

搜索结果

Search Results for " intestinal transport "

13

抑制剂 & 化合物

2

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T1244	Celiprolol hydrochloride Selecor,Selectrol,盐酸塞利洛尔	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Celiprolol hydrochloride (Selectrol) 是一种选择性肾上腺素受体调节剂，是一种选择性的和具有口服活性的β1肾上腺素受体拮抗剂，具有部分β2激动剂活性，具有降压和抗心绞痛的作用。
T35337L	Teduglutide acetate	Glucagon Receptor	GPCR/G Protein
	Teduglutide acetate 是一种 GLP-2 类似物，可使小肠黏膜肥大。它通过改变 claudin-10 的分布部分恢复小肠上皮功能，促进钠再循环以进行钠耦合葡萄糖转运和水吸收。
TP2034	Guanylin(human) Guanylin (human)
	Endogenous peptide activator of intestinal guanylyl cyclase; secreted mainly by the gastrointestinal mucosa. Regulates water and electrolyte transport in intestinal and renal epithelia.
T37312	Isotachysterol 3
	Isotachysterol 3, an analog of 1,25-dihydroxy Vitamin D3, was found to enhance intestinal calcium transport and stimulate bone calcium mobilization in anephric rats[1].
T37960	Guanylin(human) TFA
	Guanylin (human) TFA is a 15-amino acid peptide that serves as an endogenous activator of intestinal guanylate cyclase. This compound is primarily located in the gastrointestinal tract, where it regulates electrolyte and water transport in the intestinal and renal epithelia through a mechanism dependent on cyclic GMP. [1][2]
T19610	(24S)-24,25-Dihydroxyvitamin D3 (24S)-24,25-Dihydroxycholecalciferol	Vitamin	Metabolism
	(24S)-24,25-Dihydroxyvitamin D3 ((24S)-24,25-Dihydroxycholecalciferol) 具有一定的骨钙动员活性，可刺激肠道钙转运。
T37453	Butyryl-L-carnitine (chloride)
	Butyryl-L-carnitine is a butyrate ester of carnitine. It is an inhibitor of intestinal transporters, blocking carnitine uptake by the carnitine transporter and glycine transport by the amino acid transporter in human retinal pigment epithelial (HRPE) cells (IC50s = 1.5 μM and 4.6 mM, respectively).
T71340	Mizagliflozin sebacate
	Mizagliflozin sebacate is a sodium-glucose transporter inhibitor. It is expected to improve postprandial hyperglycemia by suppressing glucose absorption from the intestine with a novel mechanism of action different from that of conventional alpha-glucosidase inhibitors. Mizagliflozin blocks intestinal glucose absorption and reduce GIP secretion in rats and humans, suggesting SGLT1 glucose transport is critical for GIP release.
T72678	P-gp inhibitor 4
	P-gp inhibitor 4 是一种选择性的 P-glycoprotein 调节剂，EC50值为 94 nM。P-gp inhibitor 4 增加药物通过胃肠道屏障的能力，恢复 doxorubicin 在耐药癌细胞中的毒性。
T38011	C2 Adamantanyl Globotriaosylceramide (d18:1/2:0)
	C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide that contains an adamantanyl group in place of the fatty acyl chain. It inhibits Vero toxin binding to globotriaosylceramide in an ELISA assay when used at a concentration of 10 μM. AdaGb3 decreases cell surface expression of P-glycoprotein (P-gp) and reduces efflux of rhodamine 123 in MDCK cells. It also increases apical-to-basal transport of vinblastine in human intestinal ...
T35411	(+)-Biotin 4-Amidobenzoic Acid (sodium salt)
	(+)-Biotin 4-amidobenzoic acid is a substrate of biotinidase, which cleaves biotin amide to give biotin in vivo. Biotin is an essential coenzyme for certain carboxylases and is used to modify histones and regulate gene transcription. Biotinidase has key roles in intestinal absorption of biotin, the transport of biotin in plasma, and in the regulation of histone biotinylation. (+)-Biotin 4-amidobenzoic acid is hydrolyzed by biotinidase to release 4-aminobenzoic acid (PABA), which can be quantifie...
T76663	pTH-Related Protein (1-40) (human, mouse, rat)
	pTH-Related Protein (1-40) (human, mouse, rat) 促进大鼠肠细胞通过PTHR1受体和PKCα/β信号通路的钙吸收作用。该蛋白增加了甲状旁腺激素1受体（PTHR1）表达，提升了四种跨膜钙转运蛋白—TRPV6、CaBP-D9k、NCX1和PMCA1的水平。
T36729	Urotensin II (goby) (trifluoroacetate salt)
	Urotensin II is a peptide vasoconstrictor and agonist of the urotensin (UT) receptor (Ki= 2.06 nM for the human recombinant receptor expressed in HEK293 cells).1It stimulates intracellular calcium mobilization in HEK293 cells expressing human and rat UT (EC50s = 0.47 and 0.78 nM, respectively) but decreases intracellular calcium concentration in goby (G. mirabilis) enterocytes when used at a concentration of 500 nM.2Urotensin II (20 mU/ml) stimulates active sodium and chloride absorption across ...

化合物

Celiprolol hydrochloride

Cat.No: T1244

Synonym: Selecor,Selectrol,盐酸塞利洛尔

Target: Adrenergic Receptor

Teduglutide acetate

Cat.No: T35337L

Target: Glucagon Receptor

Guanylin(human)

Cat.No: TP2034

Synonym: Guanylin (human)

Isotachysterol 3

Cat.No: T37312

Guanylin(human) TFA

Cat.No: T37960

(24S)-24,25-Dihydroxyvitamin D3

Cat.No: T19610

Synonym: (24S)-24,25-Dihydroxycholecalciferol

Target: Vitamin

Butyryl-L-carnitine (chloride)

Cat.No: T37453

Mizagliflozin sebacate

Cat.No: T71340

P-gp inhibitor 4

Cat.No: T72678

C2 Adamantanyl Globotriaosylceramide (d18:1/2:0)

Cat.No: T38011

(+)-Biotin 4-Amidobenzoic Acid (sodium salt)

Cat.No: T35411

pTH-Related Protein (1-40) (human, mouse, rat)

Cat.No: T76663

Urotensin II (goby) (trifluoroacetate salt)

Cat.No: T36729

Cat. No.	Product Name	Target	Signaling Pathways
T4927	4-Guanidinobutanoic acid 4-GBA,4-胍基丁酸,4-Guanidinobutyric acid	Endogenous Metabolite	Metabolism
	4-Guanidinobutanoic acid (4-GBA) 是一种 L-精氨酸代谢物，已用于肠道转运研究。它已专门用于人质子偶联氨基酸转运蛋白 hPAT1。
T13490	25,26-Dihydroxyvitamin D3 25,26-Dihydroxycholecalciferol	Others	Others
	25,26-Dihydroxyvitamin D3 is a metabolite of vitamin D3 with intestinal calcium transport activity.

天然产物

4-Guanidinobutanoic acid

Cat.No: T4927

Synonym: 4-GBA,4-胍基丁酸,4-Guanidinobutyric acid

Target: Endogenous Metabolite

25,26-Dihydroxyvitamin D3

Cat.No: T13490

Synonym: 25,26-Dihydroxycholecalciferol

Target: Others

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼